17β-estradiol inhibits TGF-β-induced collagen gel contraction mediated by human Tenon fibroblasts via Smads and MAPK signaling pathways

AIM: To investigate the impact of 17β-estradiol on the collagen gels contraction (CGC) and inflammation induced by transforming growth factor (TGF)-β in human Tenon fibroblasts (HTFs). METHODS: HTFs were three-dimensionally cultivated in type I collagen-generated gels with or without TGF-β (5 ng/mL)...

詳細記述

書誌詳細
主要な著者: Cheng-Cheng Yang, Meng-Jie Liu, Yun-Ze-Peng Li, Zheng-Hua Xu, Yang Liu, Zi-Han Guo, Bin-Hui Li, Xiu-Xia Yang
フォーマット: 論文
言語:English
出版事項: Press of International Journal of Ophthalmology (IJO PRESS) 2023-09-01
シリーズ:International Journal of Ophthalmology
主題:
オンライン・アクセス:http://ies.ijo.cn/en_publish/2023/9/20230910.pdf