Stability of Imprinting and Differentiation Capacity in Naïve Human Cells Induced by Chemical Inhibition of CDK8 and CDK19

Stability of Imprinting and Differentiation Capacity in Naïve Human Cells Induced by Chemical Inhibition of CDK8 and CDK19

Pluripotent stem cells can be stabilized in vitro at different developmental states by the use of specific chemicals and soluble factors. The naïve and primed states are the best characterized pluripotency states. Naïve pluripotent stem cells (PSCs) correspond to the early pre-implantation blastocys...

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Bibliographic Details
Main Authors: Raquel Bernad, Cian J. Lynch, Rocio G. Urdinguio, Camille Stephan-Otto Attolini, Mario F. Fraga, Manuel Serrano
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
pluripotency
naïve
stem
imprinting
primordial germ cells
trophoblast
Online Access:https://www.mdpi.com/2073-4409/10/4/876

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