Pharmacokinetics of a continuous intravenous infusion of hydromorphone in healthy dogs

Pharmacokinetics of a continuous intravenous infusion of hydromorphone in healthy dogs

IntroductionDosing recommendations for hydromorphone intravenous constant rate infusion (IV CRI) are derived from simulations following IV bolus administration. While this extrapolated dose regimen has been described clinically, pharmacokinetics (PK) of hydromorphone infusions in dogs are not yet de...

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Bibliographic Details
Main Authors:	Candace Wimbish, Alex M. Lynch, Heather K. Knych, Yu Ueda, Kristen M. Messenger
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-04-01
Series:	Frontiers in Veterinary Science
Subjects:	constant rate infusion hydromorphone dog pharmacokinetics pain opioid
Online Access:	https://www.frontiersin.org/articles/10.3389/fvets.2024.1362730/full

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