Skin tags as a symptom of metabolic disorders
Skin tags are classified as benign lesions. They occur mainly on the skin of the neck, eyelids, armpits, and groin as pedicles and soft nodules. Their occurrence is associated with obesity, insulin resistance, atherogenic lipidemia, and metabolic syndrome, as well as increased risk of atherosclerosi...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Termedia Publishing House
2016-06-01
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| Series: | Przegląd Dermatologiczny |
| Subjects: | |
| Online Access: | https://www.termedia.pl/Skin-tags-as-a-symptom-of-metabolic-disorders,56,27786,1,1.html |
| _version_ | 1818683533273595904 |
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| author | Agnieszka Owczarczyk-Saczonek Waldemar Placek |
| author_facet | Agnieszka Owczarczyk-Saczonek Waldemar Placek |
| author_sort | Agnieszka Owczarczyk-Saczonek |
| collection | DOAJ |
| description | Skin tags are classified as benign lesions. They occur mainly on the skin of the neck, eyelids, armpits, and groin as pedicles and soft nodules. Their occurrence is associated with obesity, insulin resistance, atherogenic lipidemia, and metabolic syndrome, as well as increased risk of atherosclerosis. In the pathogenesis factors which are impaired in obesity, such as leptin, insulin resistance associated with obesity (IGF-1), androgens and estrogens believed to stimulate the receptors on keratinocytes and fibroblasts to grow, may play a role. In addition, these receptors are stimulated by tryptase released from the mast cells by mechanical injuries. Probably HPV plays a role as a cofactor. The dermatological literature does not provide much information about this subject, so the authors draw attention to the link between the presence of skin tags and the development of metabolic disorders. |
| first_indexed | 2024-12-17T10:36:15Z |
| format | Article |
| id | doaj.art-fd7abac74b4c43c58e9aa5ea055a7b99 |
| institution | Directory Open Access Journal |
| issn | 0033-2526 2084-9893 |
| language | English |
| last_indexed | 2024-12-17T10:36:15Z |
| publishDate | 2016-06-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Przegląd Dermatologiczny |
| spelling | doaj.art-fd7abac74b4c43c58e9aa5ea055a7b992022-12-21T21:52:24ZengTermedia Publishing HousePrzegląd Dermatologiczny0033-25262084-98932016-06-01103324024510.5114/dr.2016.6063127786Skin tags as a symptom of metabolic disordersAgnieszka Owczarczyk-SaczonekWaldemar PlacekSkin tags are classified as benign lesions. They occur mainly on the skin of the neck, eyelids, armpits, and groin as pedicles and soft nodules. Their occurrence is associated with obesity, insulin resistance, atherogenic lipidemia, and metabolic syndrome, as well as increased risk of atherosclerosis. In the pathogenesis factors which are impaired in obesity, such as leptin, insulin resistance associated with obesity (IGF-1), androgens and estrogens believed to stimulate the receptors on keratinocytes and fibroblasts to grow, may play a role. In addition, these receptors are stimulated by tryptase released from the mast cells by mechanical injuries. Probably HPV plays a role as a cofactor. The dermatological literature does not provide much information about this subject, so the authors draw attention to the link between the presence of skin tags and the development of metabolic disorders.https://www.termedia.pl/Skin-tags-as-a-symptom-of-metabolic-disorders,56,27786,1,1.htmlobesity insulin resistance skin tags |
| spellingShingle | Agnieszka Owczarczyk-Saczonek Waldemar Placek Skin tags as a symptom of metabolic disorders Przegląd Dermatologiczny obesity insulin resistance skin tags |
| title | Skin tags as a symptom of metabolic disorders |
| title_full | Skin tags as a symptom of metabolic disorders |
| title_fullStr | Skin tags as a symptom of metabolic disorders |
| title_full_unstemmed | Skin tags as a symptom of metabolic disorders |
| title_short | Skin tags as a symptom of metabolic disorders |
| title_sort | skin tags as a symptom of metabolic disorders |
| topic | obesity insulin resistance skin tags |
| url | https://www.termedia.pl/Skin-tags-as-a-symptom-of-metabolic-disorders,56,27786,1,1.html |
| work_keys_str_mv | AT agnieszkaowczarczyksaczonek skintagsasasymptomofmetabolicdisorders AT waldemarplacek skintagsasasymptomofmetabolicdisorders |