The Healing-Promoting Properties of Selected Cyclitols—A Review
Introduction: <i>Myo</i>-inositol and its derivatives cyclitols play an important role in the processes of cell regulation, signal transduction, osmoregulation, and ion channel physiology, and are a component of the cell membrane. Free cyclitols present in food or released during the deg...
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MDPI AG
2018-12-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/10/12/1891 |
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| author | Agnieszka Owczarczyk-Saczonek Lesław Bernard Lahuta Magdalena Ligor Waldemar Placek Ryszard Józef Górecki Bogusław Buszewski |
| author_facet | Agnieszka Owczarczyk-Saczonek Lesław Bernard Lahuta Magdalena Ligor Waldemar Placek Ryszard Józef Górecki Bogusław Buszewski |
| author_sort | Agnieszka Owczarczyk-Saczonek |
| collection | DOAJ |
| description | Introduction: <i>Myo</i>-inositol and its derivatives cyclitols play an important role in the processes of cell regulation, signal transduction, osmoregulation, and ion channel physiology, and are a component of the cell membrane. Free cyclitols present in food or released during the degradation of galactosyl cyclitols by bacteria (in digestive tract) show some physiological benefits. Aim: The aim of this paper is to present and analyze the documented data about curative and healing properties of cyclitols. Results and discussion: Cyclitols are well known compounds in the treatment of an accompanied diabetes insulin resistance, and also obesity and polycystic ovarian syndrome. <span style="font-variant: small-caps;">d</span>-<i>chiro</i>-Inositol deficiency exacerbates insulin resistance in the liver, muscles, and fat, while depletion of <i>myo</i>-inositol results in the development of diabetic complications. Cyclitols are successfully applied in treatment of polycystic ovarian syndrome, simultaneous are observed effective reducing of BMI, improving the hormonal profile, and increasing fertility. Moreover, cyclitols have anti-atherogenic, anti-oxidative, anti-inflammatory, and anti-cancer properties. Conclusion: The properties of cyclitols may be a good therapeutic option in the reduction of metabolically induced inflammation. Due to well drugs tolerance and low toxicity of these compounds, cyclitols are recommend for pregnant women and also for children. Another advantage is their widespread presence and easy availability, which encourages their use in medicine. |
| first_indexed | 2024-04-13T00:17:30Z |
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| language | English |
| last_indexed | 2024-04-13T00:17:30Z |
| publishDate | 2018-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-fd8113bc8d0c44af93aa071983bd8add2022-12-22T03:10:53ZengMDPI AGNutrients2072-66432018-12-011012189110.3390/nu10121891nu10121891The Healing-Promoting Properties of Selected Cyclitols—A ReviewAgnieszka Owczarczyk-Saczonek0Lesław Bernard Lahuta1Magdalena Ligor2Waldemar Placek3Ryszard Józef Górecki4Bogusław Buszewski5Department of Dermatology, Sexually Transmitted Diseases and Clinical Immunology, University of Warmia and Mazury in Olsztyn, 10-229 Olsztyn, PolandDepartment of Plant Physiology, Genetics and Biotechnology, University of Warmia and Mazury in Olsztyn, 10-229 Olsztyn, PolandDepartment of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, 87-100 Torun, PolandDepartment of Dermatology, Sexually Transmitted Diseases and Clinical Immunology, University of Warmia and Mazury in Olsztyn, 10-229 Olsztyn, PolandDepartment of Plant Physiology, Genetics and Biotechnology, University of Warmia and Mazury in Olsztyn, 10-229 Olsztyn, PolandDepartment of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, 87-100 Torun, PolandIntroduction: <i>Myo</i>-inositol and its derivatives cyclitols play an important role in the processes of cell regulation, signal transduction, osmoregulation, and ion channel physiology, and are a component of the cell membrane. Free cyclitols present in food or released during the degradation of galactosyl cyclitols by bacteria (in digestive tract) show some physiological benefits. Aim: The aim of this paper is to present and analyze the documented data about curative and healing properties of cyclitols. Results and discussion: Cyclitols are well known compounds in the treatment of an accompanied diabetes insulin resistance, and also obesity and polycystic ovarian syndrome. <span style="font-variant: small-caps;">d</span>-<i>chiro</i>-Inositol deficiency exacerbates insulin resistance in the liver, muscles, and fat, while depletion of <i>myo</i>-inositol results in the development of diabetic complications. Cyclitols are successfully applied in treatment of polycystic ovarian syndrome, simultaneous are observed effective reducing of BMI, improving the hormonal profile, and increasing fertility. Moreover, cyclitols have anti-atherogenic, anti-oxidative, anti-inflammatory, and anti-cancer properties. Conclusion: The properties of cyclitols may be a good therapeutic option in the reduction of metabolically induced inflammation. Due to well drugs tolerance and low toxicity of these compounds, cyclitols are recommend for pregnant women and also for children. Another advantage is their widespread presence and easy availability, which encourages their use in medicine.https://www.mdpi.com/2072-6643/10/12/1891cyclitols<span style="font-variant: small-caps">d</span>-<i>chiro</i>-inositol<i>myo</i>-inositol<span style="font-variant: small-caps">d</span>-pinitolinsulin resistancediabetespolycystic ovarian syndrome |
| spellingShingle | Agnieszka Owczarczyk-Saczonek Lesław Bernard Lahuta Magdalena Ligor Waldemar Placek Ryszard Józef Górecki Bogusław Buszewski The Healing-Promoting Properties of Selected Cyclitols—A Review Nutrients cyclitols <span style="font-variant: small-caps">d</span>-<i>chiro</i>-inositol <i>myo</i>-inositol <span style="font-variant: small-caps">d</span>-pinitol insulin resistance diabetes polycystic ovarian syndrome |
| title | The Healing-Promoting Properties of Selected Cyclitols—A Review |
| title_full | The Healing-Promoting Properties of Selected Cyclitols—A Review |
| title_fullStr | The Healing-Promoting Properties of Selected Cyclitols—A Review |
| title_full_unstemmed | The Healing-Promoting Properties of Selected Cyclitols—A Review |
| title_short | The Healing-Promoting Properties of Selected Cyclitols—A Review |
| title_sort | healing promoting properties of selected cyclitols a review |
| topic | cyclitols <span style="font-variant: small-caps">d</span>-<i>chiro</i>-inositol <i>myo</i>-inositol <span style="font-variant: small-caps">d</span>-pinitol insulin resistance diabetes polycystic ovarian syndrome |
| url | https://www.mdpi.com/2072-6643/10/12/1891 |
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