Periprocedural Strategies for Stroke Prevention in Patients Undergoing Transcatheter Aortic Valve Implantation

Cerebrovascular events remain a serious complication in patients undergoing transcatheter aortic valve implantation with an incidence of 2–3% at 30 days. While expanding TAVI to younger low-risk patients, prevention of periprocedural strokes becomes even more important. Different cerebral embolic pr...

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Main Authors: Matthias Linder, Moritz Seiffert
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.892956/full
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author Matthias Linder
Moritz Seiffert
Moritz Seiffert
author_facet Matthias Linder
Moritz Seiffert
Moritz Seiffert
author_sort Matthias Linder
collection DOAJ
description Cerebrovascular events remain a serious complication in patients undergoing transcatheter aortic valve implantation with an incidence of 2–3% at 30 days. While expanding TAVI to younger low-risk patients, prevention of periprocedural strokes becomes even more important. Different cerebral embolic protection devices have been tested but a clear clinical benefit has not been demonstrated in randomized trials. Due to the multifactorial aetiology with different predisposing factors, stroke prevention should include procedural and periprocedural strategies. This article aims to summarize different approaches and discuss open questions.
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spelling doaj.art-fd83db43f3294ad5bc132739be88782a2022-12-22T02:20:33ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2022-04-01910.3389/fcvm.2022.892956892956Periprocedural Strategies for Stroke Prevention in Patients Undergoing Transcatheter Aortic Valve ImplantationMatthias Linder0Moritz Seiffert1Moritz Seiffert2Department of Cardiology, University Heart & Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, GermanyDepartment of Cardiology, University Heart & Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, GermanyGerman Centre for Cardiovascular Research (DZHK), Partner Site Hamburg/Lübeck/Kiel, Hamburg, GermanyCerebrovascular events remain a serious complication in patients undergoing transcatheter aortic valve implantation with an incidence of 2–3% at 30 days. While expanding TAVI to younger low-risk patients, prevention of periprocedural strokes becomes even more important. Different cerebral embolic protection devices have been tested but a clear clinical benefit has not been demonstrated in randomized trials. Due to the multifactorial aetiology with different predisposing factors, stroke prevention should include procedural and periprocedural strategies. This article aims to summarize different approaches and discuss open questions.https://www.frontiersin.org/articles/10.3389/fcvm.2022.892956/fullanticoagulationantithrombotic therapycerebrovascular embolic protectionstrokeTAVI
spellingShingle Matthias Linder
Moritz Seiffert
Moritz Seiffert
Periprocedural Strategies for Stroke Prevention in Patients Undergoing Transcatheter Aortic Valve Implantation
Frontiers in Cardiovascular Medicine
anticoagulation
antithrombotic therapy
cerebrovascular embolic protection
stroke
TAVI
title Periprocedural Strategies for Stroke Prevention in Patients Undergoing Transcatheter Aortic Valve Implantation
title_full Periprocedural Strategies for Stroke Prevention in Patients Undergoing Transcatheter Aortic Valve Implantation
title_fullStr Periprocedural Strategies for Stroke Prevention in Patients Undergoing Transcatheter Aortic Valve Implantation
title_full_unstemmed Periprocedural Strategies for Stroke Prevention in Patients Undergoing Transcatheter Aortic Valve Implantation
title_short Periprocedural Strategies for Stroke Prevention in Patients Undergoing Transcatheter Aortic Valve Implantation
title_sort periprocedural strategies for stroke prevention in patients undergoing transcatheter aortic valve implantation
topic anticoagulation
antithrombotic therapy
cerebrovascular embolic protection
stroke
TAVI
url https://www.frontiersin.org/articles/10.3389/fcvm.2022.892956/full
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