<it>In vitro</it> correction of cystic fibrosis epithelial cell lines by small fragment homologous replacement (SFHR) technique

<it>In vitro</it> correction of cystic fibrosis epithelial cell lines by small fragment homologous replacement (SFHR) technique

<p>Abstract</p> <p>Background</p> <p>SFHR (small fragment homologous replacement)-mediated targeting is a process that has been used to correct specific mutations in mammalian cells. This process involves both chemical and cellular factors that are not yet defined. To e...

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Bibliographic Details
Main Authors: Bonifazi Emanuela, Nardone Anna, Serafino Annalucia, Bruscia Emanuela, Sangiuolo Federica, Lais Monica, Gruenert Dieter C, Novelli Giuseppe
Format: Article
Language:English
Published: BMC 2002-09-01
Series:BMC Medical Genetics
Subjects:
gene therapy
cystic fibrosis transmembrane conductance regulator (<it>CFTR</it>)
gene targeting
transmission electron microscopy (TEM)
transfection
Online Access:http://www.biomedcentral.com/1471-2350/3/8

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http://www.biomedcentral.com/1471-2350/3/8

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