The synthesis of water-soluble CDM-AM copolymer by irradiation and its solubilization effect on hydrophobic drugs

The synthesis of water-soluble CDM-AM copolymer by irradiation and its solubilization effect on hydrophobic drugs

The β-cyclodextrin-acrylamide (CDM-AM) copolymer was prepared from acrylamide and β-CD maleate (CDM) using 60Co γ-ray irradiation method. The optimized preparation conditions for the CDM-AM copolymer are as follows: CDM:AM mass ratio of 1:1; irradiation dose of 4 kGy; and using 20 mL of DMF water so...

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Bibliographic Details
Main Authors: Yong-Fu Li, Hong-Tao Tang, Si-Jing Zhou
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Designed Monomers and Polymers
Subjects:
Irradiation
Solubility
β-cyclodextrin
Copolymer
Fungicidal activity
Online Access:http://dx.doi.org/10.1080/15685551.2018.1480681

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