Distribution of Rifampicin-Resistant Tuberculosis Patients based on Presumptive Drug-Resistant Tuberculosis Criteria at Dr. Hasan Sadikin Hospital 2016–2019
Background: Diagnosis of drug-resistant tuberculosis (DR-TB) begins with identifying presumptive DR-TB patients using Xpert MTB/RIF, as a diagnostic test to detect resistance to rifampicin. The study aimed to identify the distribution of rifampicin-resistant tuberculosis (RR-TB) patients based on pr...
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| Format: | Article |
| Language: | English |
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Universitas Padjadjaran
2022-12-01
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| Series: | Althea Medical Journal |
| Subjects: | |
| Online Access: | https://journal.fk.unpad.ac.id/index.php/amj/article/view/2593 |
| _version_ | 1797952042706141184 |
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| author | Dinda Nursyafira Misyatin Arto Yuwono Soeroto Ferdy Ferdian |
| author_facet | Dinda Nursyafira Misyatin Arto Yuwono Soeroto Ferdy Ferdian |
| author_sort | Dinda Nursyafira Misyatin |
| collection | DOAJ |
| description | Background: Diagnosis of drug-resistant tuberculosis (DR-TB) begins with identifying presumptive DR-TB patients using Xpert MTB/RIF, as a diagnostic test to detect resistance to rifampicin. The study aimed to identify the distribution of rifampicin-resistant tuberculosis (RR-TB) patients based on presumptive DR-TB criteria at Dr. Hasan Sadikin General Hospital Bandung. Moreover, this study also explored the Xpert MTB/RIF Ct values.
Methods: This was a descriptive-retrospective study from 570 medical records of DR-TB patients collected at the Multidrug-resistant tuberculosis (MDR-TB) clinic of Dr. Hasan Sadikin General Hospital from 2016 to 2019. The inclusion criteria were suspected patients with the Xpert MTB/RIF Ct values in the very low-low and medium-high categories. Data were analyzed using frequency distribution.
Results: The most common presumptive DR-TB criteria among DR-TB patients were relapse cases (52.3%). Presumptive DR-TB criteria, with a high percentage result of medium-high Ct values, were category II treatment failure (80.9%).
Conclusion: Relapse case and category II treatment failure are presumptive DR-TB criteria, which need more attention from clinicians. |
| first_indexed | 2024-04-10T22:40:08Z |
| format | Article |
| id | doaj.art-fd8cf762f1ba480090e3c4e91942f989 |
| institution | Directory Open Access Journal |
| issn | 2337-4330 |
| language | English |
| last_indexed | 2024-04-10T22:40:08Z |
| publishDate | 2022-12-01 |
| publisher | Universitas Padjadjaran |
| record_format | Article |
| series | Althea Medical Journal |
| spelling | doaj.art-fd8cf762f1ba480090e3c4e91942f9892023-01-16T08:42:02ZengUniversitas PadjadjaranAlthea Medical Journal2337-43302022-12-019410.15850/amj.v9n4.25931521Distribution of Rifampicin-Resistant Tuberculosis Patients based on Presumptive Drug-Resistant Tuberculosis Criteria at Dr. Hasan Sadikin Hospital 2016–2019Dinda Nursyafira Misyatin0Arto Yuwono Soeroto1Ferdy Ferdian2Faculty of Medicine Universitas PadjadjaranDepartement of Internal Medicine, Faculty of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital, BandungDepartement of Internal Medicine, Faculty of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital, BandungBackground: Diagnosis of drug-resistant tuberculosis (DR-TB) begins with identifying presumptive DR-TB patients using Xpert MTB/RIF, as a diagnostic test to detect resistance to rifampicin. The study aimed to identify the distribution of rifampicin-resistant tuberculosis (RR-TB) patients based on presumptive DR-TB criteria at Dr. Hasan Sadikin General Hospital Bandung. Moreover, this study also explored the Xpert MTB/RIF Ct values. Methods: This was a descriptive-retrospective study from 570 medical records of DR-TB patients collected at the Multidrug-resistant tuberculosis (MDR-TB) clinic of Dr. Hasan Sadikin General Hospital from 2016 to 2019. The inclusion criteria were suspected patients with the Xpert MTB/RIF Ct values in the very low-low and medium-high categories. Data were analyzed using frequency distribution. Results: The most common presumptive DR-TB criteria among DR-TB patients were relapse cases (52.3%). Presumptive DR-TB criteria, with a high percentage result of medium-high Ct values, were category II treatment failure (80.9%). Conclusion: Relapse case and category II treatment failure are presumptive DR-TB criteria, which need more attention from clinicians.https://journal.fk.unpad.ac.id/index.php/amj/article/view/2593presumptive dr-tb criteria, tuberculosis, xpert mtb/rif ct values |
| spellingShingle | Dinda Nursyafira Misyatin Arto Yuwono Soeroto Ferdy Ferdian Distribution of Rifampicin-Resistant Tuberculosis Patients based on Presumptive Drug-Resistant Tuberculosis Criteria at Dr. Hasan Sadikin Hospital 2016–2019 Althea Medical Journal presumptive dr-tb criteria, tuberculosis, xpert mtb/rif ct values |
| title | Distribution of Rifampicin-Resistant Tuberculosis Patients based on Presumptive Drug-Resistant Tuberculosis Criteria at Dr. Hasan Sadikin Hospital 2016–2019 |
| title_full | Distribution of Rifampicin-Resistant Tuberculosis Patients based on Presumptive Drug-Resistant Tuberculosis Criteria at Dr. Hasan Sadikin Hospital 2016–2019 |
| title_fullStr | Distribution of Rifampicin-Resistant Tuberculosis Patients based on Presumptive Drug-Resistant Tuberculosis Criteria at Dr. Hasan Sadikin Hospital 2016–2019 |
| title_full_unstemmed | Distribution of Rifampicin-Resistant Tuberculosis Patients based on Presumptive Drug-Resistant Tuberculosis Criteria at Dr. Hasan Sadikin Hospital 2016–2019 |
| title_short | Distribution of Rifampicin-Resistant Tuberculosis Patients based on Presumptive Drug-Resistant Tuberculosis Criteria at Dr. Hasan Sadikin Hospital 2016–2019 |
| title_sort | distribution of rifampicin resistant tuberculosis patients based on presumptive drug resistant tuberculosis criteria at dr hasan sadikin hospital 2016 2019 |
| topic | presumptive dr-tb criteria, tuberculosis, xpert mtb/rif ct values |
| url | https://journal.fk.unpad.ac.id/index.php/amj/article/view/2593 |
| work_keys_str_mv | AT dindanursyafiramisyatin distributionofrifampicinresistanttuberculosispatientsbasedonpresumptivedrugresistanttuberculosiscriteriaatdrhasansadikinhospital20162019 AT artoyuwonosoeroto distributionofrifampicinresistanttuberculosispatientsbasedonpresumptivedrugresistanttuberculosiscriteriaatdrhasansadikinhospital20162019 AT ferdyferdian distributionofrifampicinresistanttuberculosispatientsbasedonpresumptivedrugresistanttuberculosiscriteriaatdrhasansadikinhospital20162019 |