Clinical and experimental approaches to knee cartilage lesion repair and mesenchymal stem cell chondrocyte differentiation

Clinical and experimental approaches to knee cartilage lesion repair and mesenchymal stem cell chondrocyte differentiation

Cartilage has poor regeneration capacity due to the scarcity of endogenous stem cells, its low metabolic activity and the avascular environment. Repair strategies vary widely, including microfracture, autologous or allogenic tissue implantation, and in vitro engineered tissues of autologous origin....

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Bibliographic Details
Main Authors: Fredy Montoya, Fernando Martínez, María García-Robles, Carolina Balmaceda-Aguilera, Ximena Koch, Federico Rodríguez, Carmen Silva-Álvarez, Katterine Salazar, Viviana Ulloa, Francisco Nualart
Format: Article
Language:English
Published: BMC 2013-01-01
Series:Biological Research
Subjects:
Cartilage
lesion
microfracture
stem cells
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602013000400015&lng=en&tlng=en

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