Evaluation the Expression of Endoglin (CD105) & IL-3 Level of Pregnancy Women with Antiphospholipid Syndrome
This study designed to describe the histopathology changes of human placenta for pregnancies women with APA and normal pregnancies, also to estimate placental Immunohistochemical staining (IHC) expression patterns of endoglin in pregnancies with APA compared to normal pregnancies and quantify IL-3...
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| Format: | Article |
| Language: | English |
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University of Thi-Qar
2019-05-01
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| Series: | مجلة علوم ذي قار |
| Subjects: | |
| Online Access: | https://www.jsci.utq.edu.iq/index.php/main/article/view/162 |
| _version_ | 1827738364732768256 |
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| author | Manal Salih |
| author_facet | Manal Salih |
| author_sort | Manal Salih |
| collection | DOAJ |
| description |
This study designed to describe the histopathology changes of human placenta for pregnancies women with APA
and normal pregnancies, also to estimate placental Immunohistochemical staining (IHC) expression patterns of endoglin
in pregnancies with APA compared to normal pregnancies and quantify IL-3 serum level for both groups by using
ELISA test. The histopathology results showed that arteries with degenerated media were associated with inflammatory
cells and areas of hemorrhage were associated with moderate placentitis with inflammatory cells and fibrosis; also
congested capillaries and blood vessels. The immunostaining results showed decrease in expression of endoglin in PAS
pregnancy compared than healthy pregnancy with significant difference (43.3% versus 75 % ; p ? 0.05) . Some arteries
with degeneration of sub region with hyalinization and congestion. The evaluation of the serum levels of IL-3 were
showed the elevated level in healthy pregnancy (599.15 |
| first_indexed | 2024-03-11T02:43:20Z |
| format | Article |
| id | doaj.art-fd99f10817e34e0f851989a5841da7db |
| institution | Directory Open Access Journal |
| issn | 1991-8690 2709-0256 |
| language | English |
| last_indexed | 2024-03-11T02:43:20Z |
| publishDate | 2019-05-01 |
| publisher | University of Thi-Qar |
| record_format | Article |
| series | مجلة علوم ذي قار |
| spelling | doaj.art-fd99f10817e34e0f851989a5841da7db2023-11-18T09:30:00ZengUniversity of Thi-Qarمجلة علوم ذي قار1991-86902709-02562019-05-0153Evaluation the Expression of Endoglin (CD105) & IL-3 Level of Pregnancy Women with Antiphospholipid Syndrome Manal Salih This study designed to describe the histopathology changes of human placenta for pregnancies women with APA and normal pregnancies, also to estimate placental Immunohistochemical staining (IHC) expression patterns of endoglin in pregnancies with APA compared to normal pregnancies and quantify IL-3 serum level for both groups by using ELISA test. The histopathology results showed that arteries with degenerated media were associated with inflammatory cells and areas of hemorrhage were associated with moderate placentitis with inflammatory cells and fibrosis; also congested capillaries and blood vessels. The immunostaining results showed decrease in expression of endoglin in PAS pregnancy compared than healthy pregnancy with significant difference (43.3% versus 75 % ; p ? 0.05) . Some arteries with degeneration of sub region with hyalinization and congestion. The evaluation of the serum levels of IL-3 were showed the elevated level in healthy pregnancy (599.15 https://www.jsci.utq.edu.iq/index.php/main/article/view/162CD105EndoglinAPS. |
| spellingShingle | Manal Salih Evaluation the Expression of Endoglin (CD105) & IL-3 Level of Pregnancy Women with Antiphospholipid Syndrome مجلة علوم ذي قار CD105 Endoglin APS. |
| title | Evaluation the Expression of Endoglin (CD105) & IL-3 Level of Pregnancy Women with Antiphospholipid Syndrome |
| title_full | Evaluation the Expression of Endoglin (CD105) & IL-3 Level of Pregnancy Women with Antiphospholipid Syndrome |
| title_fullStr | Evaluation the Expression of Endoglin (CD105) & IL-3 Level of Pregnancy Women with Antiphospholipid Syndrome |
| title_full_unstemmed | Evaluation the Expression of Endoglin (CD105) & IL-3 Level of Pregnancy Women with Antiphospholipid Syndrome |
| title_short | Evaluation the Expression of Endoglin (CD105) & IL-3 Level of Pregnancy Women with Antiphospholipid Syndrome |
| title_sort | evaluation the expression of endoglin cd105 il 3 level of pregnancy women with antiphospholipid syndrome |
| topic | CD105 Endoglin APS. |
| url | https://www.jsci.utq.edu.iq/index.php/main/article/view/162 |
| work_keys_str_mv | AT manalsalih evaluationtheexpressionofendoglincd105il3levelofpregnancywomenwithantiphospholipidsyndrome |