Investigation of the role of procalcitonin in early diagnosisof infective endocarditis
Introduction: Infective endocarditis (IE) is a life-threatening condition with incidence of 30-100 per million individuals. It is introduced as the 4th disease among life-threatening diseases. The present study was carried out with the aim to compare serum level of procalcitonin (PCT) at the time of...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tabriz University of Medical Sciences
2018-03-01
|
| Series: | Journal of Analytical Research in Clinical Medicine |
| Subjects: | |
| Online Access: | http://journals.tbzmed.ac.ir/JARCM/Manuscript/JARCM-6-28.pdf |
| _version_ | 1817988949414510592 |
|---|---|
| author | Zhinous Bayat –Makoo Rezvaniye Salehi Alireza Motallemi Mohammad Naghavi – Behzad Hadiseh Kavandi |
| author_facet | Zhinous Bayat –Makoo Rezvaniye Salehi Alireza Motallemi Mohammad Naghavi – Behzad Hadiseh Kavandi |
| author_sort | Zhinous Bayat –Makoo |
| collection | DOAJ |
| description | Introduction: Infective endocarditis (IE) is a life-threatening
condition with incidence of 30-100 per million individuals. It is introduced as
the 4th disease among life-threatening diseases. The present study
was carried out with the aim to compare serum level of procalcitonin (PCT) at
the time of diagnosis and at the end of treatment period among patients with IE.
Methods: In
this descriptive cross-sectional study which was performed in department of
infectious diseases and cardiology on the patients with IE, PCT level was
measured at the time of diagnosis and at the end of treatment period.
Results: In
this study, 50 patients with IE were evaluated. All of them were febrile.
Positive blood culture (PBC) was found among 36% of patients. Involvement of
tricuspid valve was detected among 34% of patients. Mean level of PCT was 3.50
± 13.78 and 14.12 ± 0.00 mg/dl at the time of diagnosis and at the end of
treatment period, respectively. Hence, the PCT level at the end of treatment
period was significantly lower than that at the time of diagnosis.
Conclusion:
PCT along with other laboratory and clinical
biomarkers can be useful in primary diagnosis and evaluation of response to
treatment among patients with IE. |
| first_indexed | 2024-04-14T00:41:03Z |
| format | Article |
| id | doaj.art-fd9d5802b11c425e87de7ada8e36ea91 |
| institution | Directory Open Access Journal |
| issn | 2345-4970 |
| language | English |
| last_indexed | 2024-04-14T00:41:03Z |
| publishDate | 2018-03-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Journal of Analytical Research in Clinical Medicine |
| spelling | doaj.art-fd9d5802b11c425e87de7ada8e36ea912022-12-22T02:22:12ZengTabriz University of Medical SciencesJournal of Analytical Research in Clinical Medicine2345-49702018-03-0161283310.15171/jarcm.2018.005JARCM_543_20180201111950Investigation of the role of procalcitonin in early diagnosisof infective endocarditisZhinous Bayat –Makoo0Rezvaniye Salehi1Alireza Motallemi2Mohammad Naghavi – Behzad3Hadiseh Kavandi4Infectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, IranCardiovascular Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Infectious Diseases, Tabriz University of Medical Sciences, Tabriz, IranStudent's Research Committee, Tabriz University of Medical Sciences, Tabriz, IranMedical Philosophy and History Research Center, Tabriz University of Medical Sciences, Tabriz, IranIntroduction: Infective endocarditis (IE) is a life-threatening condition with incidence of 30-100 per million individuals. It is introduced as the 4th disease among life-threatening diseases. The present study was carried out with the aim to compare serum level of procalcitonin (PCT) at the time of diagnosis and at the end of treatment period among patients with IE. Methods: In this descriptive cross-sectional study which was performed in department of infectious diseases and cardiology on the patients with IE, PCT level was measured at the time of diagnosis and at the end of treatment period. Results: In this study, 50 patients with IE were evaluated. All of them were febrile. Positive blood culture (PBC) was found among 36% of patients. Involvement of tricuspid valve was detected among 34% of patients. Mean level of PCT was 3.50 ± 13.78 and 14.12 ± 0.00 mg/dl at the time of diagnosis and at the end of treatment period, respectively. Hence, the PCT level at the end of treatment period was significantly lower than that at the time of diagnosis. Conclusion: PCT along with other laboratory and clinical biomarkers can be useful in primary diagnosis and evaluation of response to treatment among patients with IE.http://journals.tbzmed.ac.ir/JARCM/Manuscript/JARCM-6-28.pdfEarly DiagnosisInfective EndocarditisProcalcitonin |
| spellingShingle | Zhinous Bayat –Makoo Rezvaniye Salehi Alireza Motallemi Mohammad Naghavi – Behzad Hadiseh Kavandi Investigation of the role of procalcitonin in early diagnosisof infective endocarditis Journal of Analytical Research in Clinical Medicine Early Diagnosis Infective Endocarditis Procalcitonin |
| title | Investigation of the role of procalcitonin in early diagnosisof infective endocarditis |
| title_full | Investigation of the role of procalcitonin in early diagnosisof infective endocarditis |
| title_fullStr | Investigation of the role of procalcitonin in early diagnosisof infective endocarditis |
| title_full_unstemmed | Investigation of the role of procalcitonin in early diagnosisof infective endocarditis |
| title_short | Investigation of the role of procalcitonin in early diagnosisof infective endocarditis |
| title_sort | investigation of the role of procalcitonin in early diagnosisof infective endocarditis |
| topic | Early Diagnosis Infective Endocarditis Procalcitonin |
| url | http://journals.tbzmed.ac.ir/JARCM/Manuscript/JARCM-6-28.pdf |
| work_keys_str_mv | AT zhinousbayatmakoo investigationoftheroleofprocalcitonininearlydiagnosisofinfectiveendocarditis AT rezvaniyesalehi investigationoftheroleofprocalcitonininearlydiagnosisofinfectiveendocarditis AT alirezamotallemi investigationoftheroleofprocalcitonininearlydiagnosisofinfectiveendocarditis AT mohammadnaghavibehzad investigationoftheroleofprocalcitonininearlydiagnosisofinfectiveendocarditis AT hadisehkavandi investigationoftheroleofprocalcitonininearlydiagnosisofinfectiveendocarditis |