Quality of Life in Palliative Post-mastectomy Reconstruction: Keystone versus Rotational Flap
Background:. Late stage breast cancer presents with malignant wound causing skin infiltration, pain, bleeding, and malodour, which affect quality of life (QoL). Palliative mastectomy aims to eliminate wound symptoms and requires prolonged wound care to improve QoL. This study aimed to prospectively...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer
2021-03-01
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| Series: | Plastic and Reconstructive Surgery, Global Open |
| Online Access: | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000003457 |
| _version_ | 1818937484102336512 |
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| author | Irena Sakura Rini, MD, MARS Alberta Jesslyn Gunardi, MD Yashinta, MD Jonathan Kevin, MD Renate Parlene Marsaulina, MD Teguh Aryandono, MD Ishandono Dachlan, MD, MSc Iwan Dwiprahasto, MD, MMedSc |
| author_facet | Irena Sakura Rini, MD, MARS Alberta Jesslyn Gunardi, MD Yashinta, MD Jonathan Kevin, MD Renate Parlene Marsaulina, MD Teguh Aryandono, MD Ishandono Dachlan, MD, MSc Iwan Dwiprahasto, MD, MMedSc |
| author_sort | Irena Sakura Rini, MD, MARS |
| collection | DOAJ |
| description | Background:. Late stage breast cancer presents with malignant wound causing skin infiltration, pain, bleeding, and malodour, which affect quality of life (QoL). Palliative mastectomy aims to eliminate wound symptoms and requires prolonged wound care to improve QoL. This study aimed to prospectively investigate QoL differences in 2 alternative reconstructive methods: keystone flap and rotational flap.
Methods:. Twenty-four late stage breast cancer patients with symptoms of cancer wounds were included in this study. They were divided into 2 groups: keystone flap and rotational flap. Each patient’s QoL was evaluated using EORTC QLQ-C30 and QLQ-BR23 before and 3 weeks after surgery.
Results:. Global health post-surgery was significantly improved compared with pre-surgery in all patients (P < 0.001), across both the keystone (P = 0.018) and rotational groups (P = 0.007). Breast symptoms post-surgery were also improved compared with pre-surgery in all patients (P = 0.035). However, when analyzed per group, breast symptoms were only improved significantly in the keystone group (P = 0.013) but not in the rotational group (P = 0.575). When compared between 2 groups, future perspective post-surgery in the keystone group [100 (0–100)] was better than the rotational group [66.7 (0–100)], (P = 0.020).
Conclusions:. Reconstructive surgery after mastectomy improves QoL in late stage breast cancer patients. The keystone flap is superior to the rotational flap in improving global health and breast symptoms. |
| first_indexed | 2024-12-20T05:52:41Z |
| format | Article |
| id | doaj.art-fd9f86d30db64c7e8eabafbc24e1ff95 |
| institution | Directory Open Access Journal |
| issn | 2169-7574 |
| language | English |
| last_indexed | 2024-12-20T05:52:41Z |
| publishDate | 2021-03-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | Plastic and Reconstructive Surgery, Global Open |
| spelling | doaj.art-fd9f86d30db64c7e8eabafbc24e1ff952022-12-21T19:51:07ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742021-03-0193e345710.1097/GOX.0000000000003457202103000-00004Quality of Life in Palliative Post-mastectomy Reconstruction: Keystone versus Rotational FlapIrena Sakura Rini, MD, MARS0Alberta Jesslyn Gunardi, MD1Yashinta, MD2Jonathan Kevin, MD3Renate Parlene Marsaulina, MD4Teguh Aryandono, MD5Ishandono Dachlan, MD, MSc6Iwan Dwiprahasto, MD, MMedSc7From the * Department of Plastic Surgery, Dharmais Cancer Hospital, West Jakarta, DKI Jakarta, Indonesia;† Faculty of Medicine, Universitas Indonesia, Central Jakarta, DKI Jakarta, Indonesia;† Faculty of Medicine, Universitas Indonesia, Central Jakarta, DKI Jakarta, Indonesia;† Faculty of Medicine, Universitas Indonesia, Central Jakarta, DKI Jakarta, Indonesia;‡ Faculty of Medicine, Universitas Kristen Indonesia, Central Jakarta, DKI Jakarta, Indonesia;§ Faculty of Medicine, Gadjah Mada University, Yogyakarta, Indonesia.§ Faculty of Medicine, Gadjah Mada University, Yogyakarta, Indonesia.§ Faculty of Medicine, Gadjah Mada University, Yogyakarta, Indonesia.Background:. Late stage breast cancer presents with malignant wound causing skin infiltration, pain, bleeding, and malodour, which affect quality of life (QoL). Palliative mastectomy aims to eliminate wound symptoms and requires prolonged wound care to improve QoL. This study aimed to prospectively investigate QoL differences in 2 alternative reconstructive methods: keystone flap and rotational flap. Methods:. Twenty-four late stage breast cancer patients with symptoms of cancer wounds were included in this study. They were divided into 2 groups: keystone flap and rotational flap. Each patient’s QoL was evaluated using EORTC QLQ-C30 and QLQ-BR23 before and 3 weeks after surgery. Results:. Global health post-surgery was significantly improved compared with pre-surgery in all patients (P < 0.001), across both the keystone (P = 0.018) and rotational groups (P = 0.007). Breast symptoms post-surgery were also improved compared with pre-surgery in all patients (P = 0.035). However, when analyzed per group, breast symptoms were only improved significantly in the keystone group (P = 0.013) but not in the rotational group (P = 0.575). When compared between 2 groups, future perspective post-surgery in the keystone group [100 (0–100)] was better than the rotational group [66.7 (0–100)], (P = 0.020). Conclusions:. Reconstructive surgery after mastectomy improves QoL in late stage breast cancer patients. The keystone flap is superior to the rotational flap in improving global health and breast symptoms.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000003457 |
| spellingShingle | Irena Sakura Rini, MD, MARS Alberta Jesslyn Gunardi, MD Yashinta, MD Jonathan Kevin, MD Renate Parlene Marsaulina, MD Teguh Aryandono, MD Ishandono Dachlan, MD, MSc Iwan Dwiprahasto, MD, MMedSc Quality of Life in Palliative Post-mastectomy Reconstruction: Keystone versus Rotational Flap Plastic and Reconstructive Surgery, Global Open |
| title | Quality of Life in Palliative Post-mastectomy Reconstruction: Keystone versus Rotational Flap |
| title_full | Quality of Life in Palliative Post-mastectomy Reconstruction: Keystone versus Rotational Flap |
| title_fullStr | Quality of Life in Palliative Post-mastectomy Reconstruction: Keystone versus Rotational Flap |
| title_full_unstemmed | Quality of Life in Palliative Post-mastectomy Reconstruction: Keystone versus Rotational Flap |
| title_short | Quality of Life in Palliative Post-mastectomy Reconstruction: Keystone versus Rotational Flap |
| title_sort | quality of life in palliative post mastectomy reconstruction keystone versus rotational flap |
| url | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000003457 |
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