The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
BackgroundRheumatoid arthritis (RA) is a common systemic inflammatory autoimmune disease. The disease has a serious impact on mental health and requires more effective non-pharmacological interventions.ObjectiveThis study aims to systematically evaluate the effectiveness of patient education on psyc...
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| Format: | Article |
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Frontiers Media S.A.
2022-03-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2022.848427/full |
| _version_ | 1818306960632578048 |
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| author | Zugui Wu Yue Zhu Yi Wang Rui Zhou Xiangling Ye Zehua Chen Congcong Li Junyi Li Zixuan Ye Zhenbang Wang Wengang Liu Wengang Liu Xuemeng Xu Xuemeng Xu |
| author_facet | Zugui Wu Yue Zhu Yi Wang Rui Zhou Xiangling Ye Zehua Chen Congcong Li Junyi Li Zixuan Ye Zhenbang Wang Wengang Liu Wengang Liu Xuemeng Xu Xuemeng Xu |
| author_sort | Zugui Wu |
| collection | DOAJ |
| description | BackgroundRheumatoid arthritis (RA) is a common systemic inflammatory autoimmune disease. The disease has a serious impact on mental health and requires more effective non-pharmacological interventions.ObjectiveThis study aims to systematically evaluate the effectiveness of patient education on psychological status and clinical outcomes in rheumatoid arthritis.MethodsThis systematic review and meta-analysis was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Cochrane Library, EMBASE database, and Web of Science database were screened for articles published until November 2, 2021. Randomized controlled trials (RCTs) of patient education for RA were included. Outcomes measures included pain, physical function, disease activity, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), anxiety, depression, Arthritis Self-Efficacy (pain, other symptoms, total), and General health. For each outcome, standardized mean differences or mean differences and 95% confidence intervals (CIs) were calculated.ResultsA total of 24 RCTs (n = 2,276) were included according to the inclusion and exclusion criteria. Meta-analysis revealed a statistically significant overall effect in favor of patient education for physical function [SMD = −0.52, 95% CI (−0.96, −0.08), I2 = 93%, P = 0.02], disease activity [SMD = −1.97, 95% CI (−3.24, −0.71), I2 = 97%, P = 0.002], ASE (pain) [SMD = −1.24, 95% CI (−2.05, −0.43), I2 = 95%, P = 0.003], ASE (other symptoms) [SMD = −0.25, 95% CI (−0.41, −0.09), I2 = 25%, P = 0.002], ASE (total) [SMD = −0.67, 95% CI (−1.30, −0.05), I2 = 90%, P = 0.03], and general health [SMD = −1.11, 95% CI (−1.36, −0.86), I2 = 96%, P < 0.00001]. No effects were found for anxiety [SMD = 0.17, 95% CI (−0.64, 0.98), I2 = 82%, P = 0.68], depression [SMD = −0.18, 95% CI (−0.52, 0.15), I2 = 52%, P = 0.28], pain [SMD = −0.37, 95% CI (−0.80, 0.05), I2 = 89%, P = 0.08], and CRP [SMD = −0.27, 95% CI (−0.57, 0.02), I2 = 0%, P = 0.07].ConclusionsPatient education may be effective in improving clinical outcomes and psychological status in patients with rheumatoid arthritis. Considering the methodological limitations of the included RCTs, more high-quality and large-sample RCTs are needed to confirm this conclusion in the future.Systematic Review Registrationhttp://www.crd.york.ac.uk/prospero, identifier: CRD42021250607. |
| first_indexed | 2024-12-13T06:50:47Z |
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| id | doaj.art-fda0ee3d5a4d449aa593d3a2e1fdb259 |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-12-13T06:50:47Z |
| publishDate | 2022-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-fda0ee3d5a4d449aa593d3a2e1fdb2592022-12-21T23:56:09ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402022-03-011310.3389/fpsyt.2022.848427848427The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-AnalysisZugui Wu0Yue Zhu1Yi Wang2Rui Zhou3Xiangling Ye4Zehua Chen5Congcong Li6Junyi Li7Zixuan Ye8Zhenbang Wang9Wengang Liu10Wengang Liu11Xuemeng Xu12Xuemeng Xu13The Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, ChinaBaishui Health Center, Qujing, ChinaThe Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, ChinaGuangzhou University of Chinese Medicine, Guangzhou, ChinaThe Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, ChinaThe Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, ChinaThe Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, ChinaThe Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, ChinaThe Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, ChinaQujing Hospital of Traditional Chinese Medicine, Qujing, ChinaThe Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, ChinaGuangdong Second Traditional Chinese Medicine Hospital, Guangzhou, ChinaThe Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, ChinaGuangdong Second Traditional Chinese Medicine Hospital, Guangzhou, ChinaBackgroundRheumatoid arthritis (RA) is a common systemic inflammatory autoimmune disease. The disease has a serious impact on mental health and requires more effective non-pharmacological interventions.ObjectiveThis study aims to systematically evaluate the effectiveness of patient education on psychological status and clinical outcomes in rheumatoid arthritis.MethodsThis systematic review and meta-analysis was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Cochrane Library, EMBASE database, and Web of Science database were screened for articles published until November 2, 2021. Randomized controlled trials (RCTs) of patient education for RA were included. Outcomes measures included pain, physical function, disease activity, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), anxiety, depression, Arthritis Self-Efficacy (pain, other symptoms, total), and General health. For each outcome, standardized mean differences or mean differences and 95% confidence intervals (CIs) were calculated.ResultsA total of 24 RCTs (n = 2,276) were included according to the inclusion and exclusion criteria. Meta-analysis revealed a statistically significant overall effect in favor of patient education for physical function [SMD = −0.52, 95% CI (−0.96, −0.08), I2 = 93%, P = 0.02], disease activity [SMD = −1.97, 95% CI (−3.24, −0.71), I2 = 97%, P = 0.002], ASE (pain) [SMD = −1.24, 95% CI (−2.05, −0.43), I2 = 95%, P = 0.003], ASE (other symptoms) [SMD = −0.25, 95% CI (−0.41, −0.09), I2 = 25%, P = 0.002], ASE (total) [SMD = −0.67, 95% CI (−1.30, −0.05), I2 = 90%, P = 0.03], and general health [SMD = −1.11, 95% CI (−1.36, −0.86), I2 = 96%, P < 0.00001]. No effects were found for anxiety [SMD = 0.17, 95% CI (−0.64, 0.98), I2 = 82%, P = 0.68], depression [SMD = −0.18, 95% CI (−0.52, 0.15), I2 = 52%, P = 0.28], pain [SMD = −0.37, 95% CI (−0.80, 0.05), I2 = 89%, P = 0.08], and CRP [SMD = −0.27, 95% CI (−0.57, 0.02), I2 = 0%, P = 0.07].ConclusionsPatient education may be effective in improving clinical outcomes and psychological status in patients with rheumatoid arthritis. Considering the methodological limitations of the included RCTs, more high-quality and large-sample RCTs are needed to confirm this conclusion in the future.Systematic Review Registrationhttp://www.crd.york.ac.uk/prospero, identifier: CRD42021250607.https://www.frontiersin.org/articles/10.3389/fpsyt.2022.848427/fullpatient educationpsychotherapyrheumatoid arthritismeta-analysissystematic review |
| spellingShingle | Zugui Wu Yue Zhu Yi Wang Rui Zhou Xiangling Ye Zehua Chen Congcong Li Junyi Li Zixuan Ye Zhenbang Wang Wengang Liu Wengang Liu Xuemeng Xu Xuemeng Xu The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis Frontiers in Psychiatry patient education psychotherapy rheumatoid arthritis meta-analysis systematic review |
| title | The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis |
| title_full | The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis |
| title_fullStr | The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis |
| title_short | The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis |
| title_sort | effects of patient education on psychological status and clinical outcomes in rheumatoid arthritis a systematic review and meta analysis |
| topic | patient education psychotherapy rheumatoid arthritis meta-analysis systematic review |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2022.848427/full |
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