Optogenetic Control of Non‐Apoptotic Cell Death

Optogenetic Control of Non‐Apoptotic Cell Death

Abstract Herein, a set of optogenetic tools (designated LiPOP) that enable photoswitchable necroptosis and pyroptosis in live cells with varying kinetics, is introduced. The LiPOP tools allow reconstruction of the key molecular steps involved in these two non‐apoptotic cell death pathways by harness...

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Bibliographic Details
Main Authors: Lian He, Zixian Huang, Kai Huang, Rui Chen, Nhung T. Nguyen, Rui Wang, Xiaoli Cai, Zhiquan Huang, Stefan Siwko, Joel R. Walker, Gang Han, Yubin Zhou, Ji Jing
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Advanced Science
Subjects:
bioluminescence
necroptosis
optogenetics
pyroptosis
upconversion nanoparticles
Online Access:https://doi.org/10.1002/advs.202100424

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