Drug Nanocrystals in Oral Absorption: Factors That Influence Pharmacokinetics
Despite the safety and convenience of oral administration, poorly water-soluble drugs compromise absorption and bioavailability. These drugs can exhibit low dissolution rates, variability between fed and fasted states, difficulty permeating the mucus layer, and P-glycoprotein efflux. Drug nanocrysta...
| Hlavní autoři: | , , |
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| Médium: | Článek |
| Jazyk: | English |
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MDPI AG
2024-08-01
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| Edice: | Pharmaceutics |
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| On-line přístup: | https://www.mdpi.com/1999-4923/16/9/1141 |