Associated factors in Streptococcus bovis bacteremia and colorectal cancer
Reports suggest that between 25% and 80% of patients with Streptococcus bovis/gallolyticus bacteremia have concomitant colorectal tumors. This retrospective study was aimed to identify associations between clinical characteristics and a finding of colorectal neoplasm in patients with S. bovis bacter...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-04-01
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| Series: | Kaohsiung Journal of Medical Sciences |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1607551X16300018 |
| _version_ | 1818842164626456576 |
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| author | Cheng-En Tsai Cheng-Tang Chiu Christopher K. Rayner Keng-Liang Wu Yi-Chun Chiu Ming-Luen Hu Seng-Kee Chuah Wei-Chen Tai Chih-Ming Liang Hsin-Ming Wang |
| author_facet | Cheng-En Tsai Cheng-Tang Chiu Christopher K. Rayner Keng-Liang Wu Yi-Chun Chiu Ming-Luen Hu Seng-Kee Chuah Wei-Chen Tai Chih-Ming Liang Hsin-Ming Wang |
| author_sort | Cheng-En Tsai |
| collection | DOAJ |
| description | Reports suggest that between 25% and 80% of patients with Streptococcus bovis/gallolyticus bacteremia have concomitant colorectal tumors. This retrospective study was aimed to identify associations between clinical characteristics and a finding of colorectal neoplasm in patients with S. bovis bacteremia who had colonoscopy examination. We retrospectively reviewed the records of patients with S. bovis bacteremia from Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, between January 2004 and January 2014. Clinical data including age, sex, comorbidities, blood culture, and colonoscopy findings were collected and their relationship to a finding of colorectal cancer was examined. A total of 107 patients with S. bovis bacteremia were identified, of whom 49 (72% male; age 65 ± 12 years) were investigated with colonoscopy; 15 of these patients (30.6%) had colorectal adenocarcinoma. Female sex (p = 0.014) and a history of noncolorectal malignancy (p = 0.004) were associated with a finding of colorectal adenocarcinoma. There were no associations with age, percentage of blood cultures, or the presence of diabetes mellitus, chronic liver disease, heart disease, or end-stage renal disease. Our results show that S. bovis bacteremia is associated with the presence of colorectal adenocarcinoma, especially in female patients, and concomitant existence of other malignancies. |
| first_indexed | 2024-12-19T04:37:37Z |
| format | Article |
| id | doaj.art-fdaa5450848746f3873a8cce223fa2d7 |
| institution | Directory Open Access Journal |
| issn | 1607-551X |
| language | English |
| last_indexed | 2024-12-19T04:37:37Z |
| publishDate | 2016-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Kaohsiung Journal of Medical Sciences |
| spelling | doaj.art-fdaa5450848746f3873a8cce223fa2d72022-12-21T20:35:43ZengWileyKaohsiung Journal of Medical Sciences1607-551X2016-04-0132419620010.1016/j.kjms.2016.03.003Associated factors in Streptococcus bovis bacteremia and colorectal cancerCheng-En Tsai0Cheng-Tang Chiu1Christopher K. Rayner2Keng-Liang Wu3Yi-Chun Chiu4Ming-Luen Hu5Seng-Kee Chuah6Wei-Chen Tai7Chih-Ming Liang8Hsin-Ming Wang9Division of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, TaiwanDivision of Hepatogastroenterology, Department of Internal Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan, TaiwanDiscipline of Medicine, Royal Adelaide Hospital, University of Adelaide, Adelaide, AustraliaDivision of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, TaiwanDivision of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, TaiwanDivision of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, TaiwanDivision of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, TaiwanDivision of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, TaiwanDivision of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, TaiwanDivision of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, TaiwanReports suggest that between 25% and 80% of patients with Streptococcus bovis/gallolyticus bacteremia have concomitant colorectal tumors. This retrospective study was aimed to identify associations between clinical characteristics and a finding of colorectal neoplasm in patients with S. bovis bacteremia who had colonoscopy examination. We retrospectively reviewed the records of patients with S. bovis bacteremia from Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, between January 2004 and January 2014. Clinical data including age, sex, comorbidities, blood culture, and colonoscopy findings were collected and their relationship to a finding of colorectal cancer was examined. A total of 107 patients with S. bovis bacteremia were identified, of whom 49 (72% male; age 65 ± 12 years) were investigated with colonoscopy; 15 of these patients (30.6%) had colorectal adenocarcinoma. Female sex (p = 0.014) and a history of noncolorectal malignancy (p = 0.004) were associated with a finding of colorectal adenocarcinoma. There were no associations with age, percentage of blood cultures, or the presence of diabetes mellitus, chronic liver disease, heart disease, or end-stage renal disease. Our results show that S. bovis bacteremia is associated with the presence of colorectal adenocarcinoma, especially in female patients, and concomitant existence of other malignancies.http://www.sciencedirect.com/science/article/pii/S1607551X16300018BacteremiaColorectal adenocarcinomaStreptococcus bovis |
| spellingShingle | Cheng-En Tsai Cheng-Tang Chiu Christopher K. Rayner Keng-Liang Wu Yi-Chun Chiu Ming-Luen Hu Seng-Kee Chuah Wei-Chen Tai Chih-Ming Liang Hsin-Ming Wang Associated factors in Streptococcus bovis bacteremia and colorectal cancer Kaohsiung Journal of Medical Sciences Bacteremia Colorectal adenocarcinoma Streptococcus bovis |
| title | Associated factors in Streptococcus bovis bacteremia and colorectal cancer |
| title_full | Associated factors in Streptococcus bovis bacteremia and colorectal cancer |
| title_fullStr | Associated factors in Streptococcus bovis bacteremia and colorectal cancer |
| title_full_unstemmed | Associated factors in Streptococcus bovis bacteremia and colorectal cancer |
| title_short | Associated factors in Streptococcus bovis bacteremia and colorectal cancer |
| title_sort | associated factors in streptococcus bovis bacteremia and colorectal cancer |
| topic | Bacteremia Colorectal adenocarcinoma Streptococcus bovis |
| url | http://www.sciencedirect.com/science/article/pii/S1607551X16300018 |
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