Research Progresses of Circulating Tumor Cells in Diagnosis and Treatment of 
Early Lung Cancer

As one of the important liquid biopsies, circulating tumor cells (CTCs) shows more and more clinical values in the treatment of lung cancer such as diagnostic screening, treatment evaluation, postoperative monitoring, and prognosis predicting etc. A large number of small pulmonary nodules patients a...

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Main Authors: Xinchun DUAN, Zhidong LIU, Shaofa XU
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2017-10-01
Series:Chinese Journal of Lung Cancer
Subjects:
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2017.10.07
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author Xinchun DUAN
Zhidong LIU
Shaofa XU
author_facet Xinchun DUAN
Zhidong LIU
Shaofa XU
author_sort Xinchun DUAN
collection DOAJ
description As one of the important liquid biopsies, circulating tumor cells (CTCs) shows more and more clinical values in the treatment of lung cancer such as diagnostic screening, treatment evaluation, postoperative monitoring, and prognosis predicting etc. A large number of small pulmonary nodules patients are detected when screening the high risk population of lung cancer. However, small lung nodules are not equal to lung cancer, and 90%-95% of them are benign lesion, therefore, to accurately and correctly differentiate whether it is benign or malignant when patients firstly detected and treat a small pulmonary nodule is become a new opportunity and challenge for clinician. With the improvement of CTCs detection technology, whether it will play an important role in early differential diagnosis of lung cancer. And whether it will have clinical significance to early lung cancer surgery operations. These require further researches and explorations so as to achieve clinical transformation in the future.
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spelling doaj.art-fdad1de3abbb4a10867b54998399daf82022-12-21T23:21:45ZzhoChinese Anti-Cancer Association; Chinese Antituberculosis AssociationChinese Journal of Lung Cancer1009-34191999-61872017-10-01201070370910.3779/j.issn.1009-3419.2017.10.07Research Progresses of Circulating Tumor Cells in Diagnosis and Treatment of 
Early Lung CancerXinchun DUAN0Zhidong LIU1Shaofa XU2Department of Thoracic Surgery, Beijing Chest Hospital, Capital Medical University, Beijing 101149, ChinaDepartment of Thoracic Surgery, Beijing Chest Hospital, Capital Medical University, Beijing 101149, ChinaDepartment of Thoracic Surgery, Beijing Chest Hospital, Capital Medical University, Beijing 101149, ChinaAs one of the important liquid biopsies, circulating tumor cells (CTCs) shows more and more clinical values in the treatment of lung cancer such as diagnostic screening, treatment evaluation, postoperative monitoring, and prognosis predicting etc. A large number of small pulmonary nodules patients are detected when screening the high risk population of lung cancer. However, small lung nodules are not equal to lung cancer, and 90%-95% of them are benign lesion, therefore, to accurately and correctly differentiate whether it is benign or malignant when patients firstly detected and treat a small pulmonary nodule is become a new opportunity and challenge for clinician. With the improvement of CTCs detection technology, whether it will play an important role in early differential diagnosis of lung cancer. And whether it will have clinical significance to early lung cancer surgery operations. These require further researches and explorations so as to achieve clinical transformation in the future.http://dx.doi.org/10.3779/j.issn.1009-3419.2017.10.07Circulating tumor cellsLiquid biopsySmall pulmonary nodulesLung neoplasmDiagnosis
spellingShingle Xinchun DUAN
Zhidong LIU
Shaofa XU
Research Progresses of Circulating Tumor Cells in Diagnosis and Treatment of 
Early Lung Cancer
Chinese Journal of Lung Cancer
Circulating tumor cells
Liquid biopsy
Small pulmonary nodules
Lung neoplasm
Diagnosis
title Research Progresses of Circulating Tumor Cells in Diagnosis and Treatment of 
Early Lung Cancer
title_full Research Progresses of Circulating Tumor Cells in Diagnosis and Treatment of 
Early Lung Cancer
title_fullStr Research Progresses of Circulating Tumor Cells in Diagnosis and Treatment of 
Early Lung Cancer
title_full_unstemmed Research Progresses of Circulating Tumor Cells in Diagnosis and Treatment of 
Early Lung Cancer
title_short Research Progresses of Circulating Tumor Cells in Diagnosis and Treatment of 
Early Lung Cancer
title_sort research progresses of circulating tumor cells in diagnosis and treatment of 
early lung cancer
topic Circulating tumor cells
Liquid biopsy
Small pulmonary nodules
Lung neoplasm
Diagnosis
url http://dx.doi.org/10.3779/j.issn.1009-3419.2017.10.07
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