Plasma heavy metal levels correlate with deregulated gene expression of detoxifying enzymes in osteoporotic patients

Abstract Heavy metal levels appear to be associated with low bone mineral density (BMD) and the consequent osteoporosis risk, but the relationship with the disease has not been clearly defined. The altered expression pattern of numerous genes, including detoxifying genes, seems to play a pivotal rol...

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Bibliographic Details
Main Authors: V. V. Visconti, B. Gasperini, C. Greggi, B. Battistini, A. Messina, M. Renzi, K. Bakhtafrouz, R. Iundusi, A. Botta, L. Palombi, U. Tarantino
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-37410-8