Kaiso differentially regulates components of the Notch signaling pathway in intestinal cells

Kaiso differentially regulates components of the Notch signaling pathway in intestinal cells

Abstract Background In mammalian intestines, Notch signaling plays a critical role in mediating cell fate decisions; it promotes the absorptive (or enterocyte) cell fate, while concomitantly inhibiting the secretory cell fate (i.e. goblet, Paneth and enteroendocrine cells). We recently reported that...

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Bibliographic Details
Main Authors: Shaiya C. Robinson, Kristina Klobucar, Christina C. Pierre, Amna Ansari, Svetlana Zhenilo, Egor Prokhortchouk, Juliet M. Daniel
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Cell Communication and Signaling
Subjects:
Kaiso
Notch
Dll-1
Jagged-1
Intestinal homeostasis
Intestinal cell fates
Online Access:http://link.springer.com/article/10.1186/s12964-017-0178-x

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