4D-Flow Cardiovascular Magnetic Resonance Sequence for Aortic Assessment: Multi-Vendor and Multi-Magnetic Field Reproducibility in Healthy Volunteers
Objectives: Four-dimensional (4D) flow cardiac magnetic resonance (CMR) represents an emerging technique for non-invasive evaluation of the aortic flow. The aim of this study was to investigate a 4D-flow CMR sequence for the assessment of thoracic aorta comparing different vendors and different magn...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-04-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/8/2960 |
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| author | Bruna Punzo Brigida Ranieri Liberatore Tramontano Ornella Affinito Monica Franzese Eduardo Bossone Luca Saba Carlo Cavaliere Filippo Cademartiri |
| author_facet | Bruna Punzo Brigida Ranieri Liberatore Tramontano Ornella Affinito Monica Franzese Eduardo Bossone Luca Saba Carlo Cavaliere Filippo Cademartiri |
| author_sort | Bruna Punzo |
| collection | DOAJ |
| description | Objectives: Four-dimensional (4D) flow cardiac magnetic resonance (CMR) represents an emerging technique for non-invasive evaluation of the aortic flow. The aim of this study was to investigate a 4D-flow CMR sequence for the assessment of thoracic aorta comparing different vendors and different magnetic fields of MR scanner in fifteen healthy volunteers. Methods: CMR was performed on three different MRI scanners: one at 1.5 T and two at 3 T. Flow parameters and planar wall shear stress (WSS) were extracted from six transversal planes along the full thoracic aorta by three operators. Inter-vendor comparability as well as scan–rescan, intra- and interobserver reproducibility were examined. Results: A high heterogeneity was found in the comparisons for each operator and for each scanner in the six transversal planes analysis (Friedman rank-sum test; <i>p</i>-value ≤ 0.05). Among all, the most reproducible measures were extracted for the sinotubular junction plane and for the flow parameters. Conclusions: Our results suggest that standardized procedures have to be defined to make more comparable and reproducible 4D-flow parameters and mainly, clinical impactfulness. Further studies on sequences development are needed to validate 4D-flow MRI assessment across vendors and magnetic fields also compared to a missing gold standard. |
| first_indexed | 2024-03-11T04:53:32Z |
| format | Article |
| id | doaj.art-fdb5011795a04a3e8dcd03102175e6c5 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T04:53:32Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-fdb5011795a04a3e8dcd03102175e6c52023-11-17T19:50:53ZengMDPI AGJournal of Clinical Medicine2077-03832023-04-01128296010.3390/jcm120829604D-Flow Cardiovascular Magnetic Resonance Sequence for Aortic Assessment: Multi-Vendor and Multi-Magnetic Field Reproducibility in Healthy VolunteersBruna Punzo0Brigida Ranieri1Liberatore Tramontano2Ornella Affinito3Monica Franzese4Eduardo Bossone5Luca Saba6Carlo Cavaliere7Filippo Cademartiri8IRCCS SYNLAB SDN, Via Emanuele Gianturco 113, 80143 Naples, ItalyIRCCS SYNLAB SDN, Via Emanuele Gianturco 113, 80143 Naples, ItalyIRCCS SYNLAB SDN, Via Emanuele Gianturco 113, 80143 Naples, ItalyIRCCS SYNLAB SDN, Via Emanuele Gianturco 113, 80143 Naples, ItalyIRCCS SYNLAB SDN, Via Emanuele Gianturco 113, 80143 Naples, ItalyDepartment of Public Health, “Federico II” University of Naples, 80131 Naples, ItalyDepartment of Radiology, Azienda Ospedaliero-Universitaria (A.O.U.) di Cagliari, 09123 Cagliari, ItalyIRCCS SYNLAB SDN, Via Emanuele Gianturco 113, 80143 Naples, ItalyDepartment of Radiology, Fondazione Monasterio/CNR, 56124 Pisa, ItalyObjectives: Four-dimensional (4D) flow cardiac magnetic resonance (CMR) represents an emerging technique for non-invasive evaluation of the aortic flow. The aim of this study was to investigate a 4D-flow CMR sequence for the assessment of thoracic aorta comparing different vendors and different magnetic fields of MR scanner in fifteen healthy volunteers. Methods: CMR was performed on three different MRI scanners: one at 1.5 T and two at 3 T. Flow parameters and planar wall shear stress (WSS) were extracted from six transversal planes along the full thoracic aorta by three operators. Inter-vendor comparability as well as scan–rescan, intra- and interobserver reproducibility were examined. Results: A high heterogeneity was found in the comparisons for each operator and for each scanner in the six transversal planes analysis (Friedman rank-sum test; <i>p</i>-value ≤ 0.05). Among all, the most reproducible measures were extracted for the sinotubular junction plane and for the flow parameters. Conclusions: Our results suggest that standardized procedures have to be defined to make more comparable and reproducible 4D-flow parameters and mainly, clinical impactfulness. Further studies on sequences development are needed to validate 4D-flow MRI assessment across vendors and magnetic fields also compared to a missing gold standard.https://www.mdpi.com/2077-0383/12/8/2960cardiac magnetic resonance4D-flowaortaphase-contrast CMRaortic blood flow |
| spellingShingle | Bruna Punzo Brigida Ranieri Liberatore Tramontano Ornella Affinito Monica Franzese Eduardo Bossone Luca Saba Carlo Cavaliere Filippo Cademartiri 4D-Flow Cardiovascular Magnetic Resonance Sequence for Aortic Assessment: Multi-Vendor and Multi-Magnetic Field Reproducibility in Healthy Volunteers Journal of Clinical Medicine cardiac magnetic resonance 4D-flow aorta phase-contrast CMR aortic blood flow |
| title | 4D-Flow Cardiovascular Magnetic Resonance Sequence for Aortic Assessment: Multi-Vendor and Multi-Magnetic Field Reproducibility in Healthy Volunteers |
| title_full | 4D-Flow Cardiovascular Magnetic Resonance Sequence for Aortic Assessment: Multi-Vendor and Multi-Magnetic Field Reproducibility in Healthy Volunteers |
| title_fullStr | 4D-Flow Cardiovascular Magnetic Resonance Sequence for Aortic Assessment: Multi-Vendor and Multi-Magnetic Field Reproducibility in Healthy Volunteers |
| title_full_unstemmed | 4D-Flow Cardiovascular Magnetic Resonance Sequence for Aortic Assessment: Multi-Vendor and Multi-Magnetic Field Reproducibility in Healthy Volunteers |
| title_short | 4D-Flow Cardiovascular Magnetic Resonance Sequence for Aortic Assessment: Multi-Vendor and Multi-Magnetic Field Reproducibility in Healthy Volunteers |
| title_sort | 4d flow cardiovascular magnetic resonance sequence for aortic assessment multi vendor and multi magnetic field reproducibility in healthy volunteers |
| topic | cardiac magnetic resonance 4D-flow aorta phase-contrast CMR aortic blood flow |
| url | https://www.mdpi.com/2077-0383/12/8/2960 |
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