Enteral Nutrition Supplemented with Transforming Growth Factor-β, Colostrum, Probiotics, and Other Nutritional Compounds in the Treatment of Patients with Inflammatory Bowel Disease

Enteral nutrition seems to play a significant role in the treatment of both adults and children with active Crohn’s disease, and to a lesser degree in the treatment of patients with active ulcerative colitis. The inclusion of some special factors in the enteral nutrition formulas might increase the...

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Main Authors: John K. Triantafillidis, Maria Tzouvala, Eleni Triantafyllidi
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/12/4/1048
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author John K. Triantafillidis
Maria Tzouvala
Eleni Triantafyllidi
author_facet John K. Triantafillidis
Maria Tzouvala
Eleni Triantafyllidi
author_sort John K. Triantafillidis
collection DOAJ
description Enteral nutrition seems to play a significant role in the treatment of both adults and children with active Crohn’s disease, and to a lesser degree in the treatment of patients with active ulcerative colitis. The inclusion of some special factors in the enteral nutrition formulas might increase the rate of the efficacy. Actually, enteral nutrition enriched in Transforming Growth Factor-β reduced the activity index and maintained remission in patients with Crohn’s disease. In addition, a number of experimental animal studies have shown that colostrum exerts a significantly positive result. Probiotics of a special type and a certain dosage could also reduce the inflammatory process in patients with active ulcerative colitis. Therefore, the addition of these factors in an enteral nutrition formula might increase its effectiveness. Although the use of these formulas is not supported by large clinical trials, it could be argued that their administration in selected cases as an exclusive diet or in combination with the drugs used in patients with inflammatory bowel disease could benefit the patient. In this review, the authors provide an update on the role of enteral nutrition, supplemented with Transforming Growth Factor-β, colostrum, and probiotics in patients with inflammatory bowel disease.
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spelling doaj.art-fdb5634437df421ba5af74f6b4b0cb182023-11-19T21:16:50ZengMDPI AGNutrients2072-66432020-04-01124104810.3390/nu12041048Enteral Nutrition Supplemented with Transforming Growth Factor-β, Colostrum, Probiotics, and Other Nutritional Compounds in the Treatment of Patients with Inflammatory Bowel DiseaseJohn K. Triantafillidis0Maria Tzouvala1Eleni Triantafyllidi2“Metropolitan General” Hospital, ZC 15562 Holargos, GreeceDepartment of Gastroenterology “St Panteleimon” General Hospital, ZC 18454 Nicea, Greece“Metropolitan General” Hospital, ZC 15562 Holargos, GreeceEnteral nutrition seems to play a significant role in the treatment of both adults and children with active Crohn’s disease, and to a lesser degree in the treatment of patients with active ulcerative colitis. The inclusion of some special factors in the enteral nutrition formulas might increase the rate of the efficacy. Actually, enteral nutrition enriched in Transforming Growth Factor-β reduced the activity index and maintained remission in patients with Crohn’s disease. In addition, a number of experimental animal studies have shown that colostrum exerts a significantly positive result. Probiotics of a special type and a certain dosage could also reduce the inflammatory process in patients with active ulcerative colitis. Therefore, the addition of these factors in an enteral nutrition formula might increase its effectiveness. Although the use of these formulas is not supported by large clinical trials, it could be argued that their administration in selected cases as an exclusive diet or in combination with the drugs used in patients with inflammatory bowel disease could benefit the patient. In this review, the authors provide an update on the role of enteral nutrition, supplemented with Transforming Growth Factor-β, colostrum, and probiotics in patients with inflammatory bowel disease.https://www.mdpi.com/2072-6643/12/4/1048enteral nutritionTGF-βcolostrumprobioticsCrohn’s diseaseulcerative colitis
spellingShingle John K. Triantafillidis
Maria Tzouvala
Eleni Triantafyllidi
Enteral Nutrition Supplemented with Transforming Growth Factor-β, Colostrum, Probiotics, and Other Nutritional Compounds in the Treatment of Patients with Inflammatory Bowel Disease
Nutrients
enteral nutrition
TGF-β
colostrum
probiotics
Crohn’s disease
ulcerative colitis
title Enteral Nutrition Supplemented with Transforming Growth Factor-β, Colostrum, Probiotics, and Other Nutritional Compounds in the Treatment of Patients with Inflammatory Bowel Disease
title_full Enteral Nutrition Supplemented with Transforming Growth Factor-β, Colostrum, Probiotics, and Other Nutritional Compounds in the Treatment of Patients with Inflammatory Bowel Disease
title_fullStr Enteral Nutrition Supplemented with Transforming Growth Factor-β, Colostrum, Probiotics, and Other Nutritional Compounds in the Treatment of Patients with Inflammatory Bowel Disease
title_full_unstemmed Enteral Nutrition Supplemented with Transforming Growth Factor-β, Colostrum, Probiotics, and Other Nutritional Compounds in the Treatment of Patients with Inflammatory Bowel Disease
title_short Enteral Nutrition Supplemented with Transforming Growth Factor-β, Colostrum, Probiotics, and Other Nutritional Compounds in the Treatment of Patients with Inflammatory Bowel Disease
title_sort enteral nutrition supplemented with transforming growth factor β colostrum probiotics and other nutritional compounds in the treatment of patients with inflammatory bowel disease
topic enteral nutrition
TGF-β
colostrum
probiotics
Crohn’s disease
ulcerative colitis
url https://www.mdpi.com/2072-6643/12/4/1048
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