Investigating the Effects of a New Peptide, Derived from the <i>Enterolobium contortisiliquum</i> Proteinase Inhibitor (EcTI), on Inflammation, Remodeling, and Oxidative Stress in an Experimental Mouse Model of Asthma–Chronic Obstructive Pulmonary Disease Overlap (ACO)

Investigating the Effects of a New Peptide, Derived from the <i>Enterolobium contortisiliquum</i> Proteinase Inhibitor (EcTI), on Inflammation, Remodeling, and Oxidative Stress in an Experimental Mouse Model of Asthma–Chronic Obstructive Pulmonary Disease Overlap (ACO)

The synthesized peptide derived from <i>Enterolobium contortisiliquum</i> (pep3-EcTI) has been associated with potent anti-inflammatory and antioxidant effects, and it may be a potential new treatment for asthma–COPD overlap—ACO). Purpose: To investigate the primary sequence effects of p...

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Bibliographic Details
Main Authors: Jéssica Anastácia Silva Barbosa, Luana Laura Sales da Silva, Juliana Morelli Lopes Gonçalves João, Elaine Cristina de Campos, Silvia Fukuzaki, Leandro do Nascimento Camargo, Tabata Maruyama dos Santos, Henrique Tibucheski dos Santos, Suellen Karoline Moreira Bezerra, Beatriz Mangueira Saraiva-Romanholo, Fernanda Degobbi Tenório Quirino dos Santos Lopes, Camila Ramalho Bonturi, Maria Luiza Vilela Oliva, Edna Aparecida Leick, Renato Fraga Righetti, Iolanda de Fátima Lopes Calvo Tibério
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
asthma–chronic obstructive pulmonary disease overlap
protease inhibitors
inflammation
airway remodeling
oxidative stress
Online Access:https://www.mdpi.com/1422-0067/24/19/14710

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