Crystal structure and Hirshfeld surface analysis of 2-chloro-N-(4-methoxyphenyl)acetamide
In the title molecule, C9H10ClNO2, the methoxy group lies very close to the plane of the phenyl ring while the acetamido group is twisted out of this plane by 28.87 (5)°. In the crystal, a three-dimensional structure is generated by N—H...O, C—H...O and C—H...Cl hydrogen bonds plus C—H...π(ring) int...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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International Union of Crystallography
2022-07-01
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| Series: | Acta Crystallographica Section E: Crystallographic Communications |
| Subjects: | |
| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S205698902200576X |
| _version_ | 1818469444174741504 |
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| author | Mohcine Missioui Walid Guerrab Intissar Nchioua Abderrazzak El Moutaouakil Ala Allah Camille Kalonji Mubengayi Abdulsalam Alsubari Joel T. Mague Youssef Ramli |
| author_facet | Mohcine Missioui Walid Guerrab Intissar Nchioua Abderrazzak El Moutaouakil Ala Allah Camille Kalonji Mubengayi Abdulsalam Alsubari Joel T. Mague Youssef Ramli |
| author_sort | Mohcine Missioui |
| collection | DOAJ |
| description | In the title molecule, C9H10ClNO2, the methoxy group lies very close to the plane of the phenyl ring while the acetamido group is twisted out of this plane by 28.87 (5)°. In the crystal, a three-dimensional structure is generated by N—H...O, C—H...O and C—H...Cl hydrogen bonds plus C—H...π(ring) interactions. A Hirshfeld surface analysis of the intermolecular interactions was performed and indicated that C...H/H...C interactions make the largest contribution to the surface area (33.4%). |
| first_indexed | 2024-04-13T21:23:44Z |
| format | Article |
| id | doaj.art-fdb5cff2fbb84611a5de938692c9722a |
| institution | Directory Open Access Journal |
| issn | 2056-9890 |
| language | English |
| last_indexed | 2024-04-13T21:23:44Z |
| publishDate | 2022-07-01 |
| publisher | International Union of Crystallography |
| record_format | Article |
| series | Acta Crystallographica Section E: Crystallographic Communications |
| spelling | doaj.art-fdb5cff2fbb84611a5de938692c9722a2022-12-22T02:29:24ZengInternational Union of CrystallographyActa Crystallographica Section E: Crystallographic Communications2056-98902022-07-0178768769010.1107/S205698902200576Xvm2264Crystal structure and Hirshfeld surface analysis of 2-chloro-N-(4-methoxyphenyl)acetamideMohcine Missioui0Walid Guerrab1Intissar Nchioua2Abderrazzak El Moutaouakil Ala Allah3Camille Kalonji Mubengayi4Abdulsalam Alsubari5Joel T. Mague6Youssef Ramli7Laboratory of Medicinal Chemistry, Drug Sciences Research Center, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, MoroccoLaboratory of Medicinal Chemistry, Drug Sciences Research Center, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, MoroccoLaboratory of Medicinal Chemistry, Drug Sciences Research Center, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, MoroccoLaboratory of Medicinal Chemistry, Drug Sciences Research Center, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, MoroccoLaboratoire de Chimie et Biochimie, Institut Superieur des Techniques Medicales de Kinshasa, Republique Democratique du , CongoLaboratory of Medicinal Chemistry, Faculty of Clinical Pharmacy, 21 September University, YemenDepartment of Chemistry, Tulane University, New Orleans, LA 70118, USALaboratory of Medicinal Chemistry, Drug Sciences Research Center, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, MoroccoIn the title molecule, C9H10ClNO2, the methoxy group lies very close to the plane of the phenyl ring while the acetamido group is twisted out of this plane by 28.87 (5)°. In the crystal, a three-dimensional structure is generated by N—H...O, C—H...O and C—H...Cl hydrogen bonds plus C—H...π(ring) interactions. A Hirshfeld surface analysis of the intermolecular interactions was performed and indicated that C...H/H...C interactions make the largest contribution to the surface area (33.4%).http://scripts.iucr.org/cgi-bin/paper?S205698902200576Xcrystal structurehydrogen bondc—h...π(ring) interactionacetamidehirshfeld surface |
| spellingShingle | Mohcine Missioui Walid Guerrab Intissar Nchioua Abderrazzak El Moutaouakil Ala Allah Camille Kalonji Mubengayi Abdulsalam Alsubari Joel T. Mague Youssef Ramli Crystal structure and Hirshfeld surface analysis of 2-chloro-N-(4-methoxyphenyl)acetamide Acta Crystallographica Section E: Crystallographic Communications crystal structure hydrogen bond c—h...π(ring) interaction acetamide hirshfeld surface |
| title | Crystal structure and Hirshfeld surface analysis of 2-chloro-N-(4-methoxyphenyl)acetamide |
| title_full | Crystal structure and Hirshfeld surface analysis of 2-chloro-N-(4-methoxyphenyl)acetamide |
| title_fullStr | Crystal structure and Hirshfeld surface analysis of 2-chloro-N-(4-methoxyphenyl)acetamide |
| title_full_unstemmed | Crystal structure and Hirshfeld surface analysis of 2-chloro-N-(4-methoxyphenyl)acetamide |
| title_short | Crystal structure and Hirshfeld surface analysis of 2-chloro-N-(4-methoxyphenyl)acetamide |
| title_sort | crystal structure and hirshfeld surface analysis of 2 chloro n 4 methoxyphenyl acetamide |
| topic | crystal structure hydrogen bond c—h...π(ring) interaction acetamide hirshfeld surface |
| url | http://scripts.iucr.org/cgi-bin/paper?S205698902200576X |
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