Chalcogenide Glass Optical Waveguides for Infrared Biosensing
Due to the remarkable properties of chalcogenide (Chg) glasses, Chg optical waveguides should play a significant role in the development of optical biosensors. This paper describes the fabrication and properties of chalcogenide fibres and planar waveguides. Using optical fibre transparent in the mid...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2009-09-01
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| Series: | Sensors |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1424-8220/9/9/7398/ |
| _version_ | 1828153443797172224 |
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| author | Bruno Bureau Florent Colas Chantal Compère Kiyoyuki Yanakata Olivier Loreal Jenny Le Person Hervé Lhermite Joël Charrier Catherine Boussard-Pledel Satoru Inoue Koji Hyodo Virginie Nazabal Julie Keirsse Marie-Laure Anne |
| author_facet | Bruno Bureau Florent Colas Chantal Compère Kiyoyuki Yanakata Olivier Loreal Jenny Le Person Hervé Lhermite Joël Charrier Catherine Boussard-Pledel Satoru Inoue Koji Hyodo Virginie Nazabal Julie Keirsse Marie-Laure Anne |
| author_sort | Bruno Bureau |
| collection | DOAJ |
| description | Due to the remarkable properties of chalcogenide (Chg) glasses, Chg optical waveguides should play a significant role in the development of optical biosensors. This paper describes the fabrication and properties of chalcogenide fibres and planar waveguides. Using optical fibre transparent in the mid-infrared spectral range we have developed a biosensor that can collect information on whole metabolism alterations, rapidly and in situ. Thanks to this sensor it is possible to collect infrared spectra by remote spectroscopy, by simple contact with the sample. In this way, we tried to determine spectral modifications due, on the one hand, to cerebral metabolism alterations caused by a transient focal ischemia in the rat brain and, in the other hand, starvation in the mouse liver. We also applied a microdialysis method, a well known technique for in vivo brain metabolism studies, as reference. In the field of integrated microsensors, reactive ion etching was used to pattern rib waveguides between 2 and 300 μm wide. This technique was used to fabricate Y optical junctions for optical interconnections on chalcogenide amorphous films, which can potentially increase the sensitivity and stability of an optical micro-sensor. The first tests were also carried out to functionalise the Chg planar waveguides with the aim of using them as (bio)sensors. |
| first_indexed | 2024-04-11T22:26:11Z |
| format | Article |
| id | doaj.art-fdb679c6332447379b5f9f71f342d723 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-11T22:26:11Z |
| publishDate | 2009-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-fdb679c6332447379b5f9f71f342d7232022-12-22T03:59:44ZengMDPI AGSensors1424-82202009-09-01997398741110.3390/s90907398Chalcogenide Glass Optical Waveguides for Infrared BiosensingBruno BureauFlorent ColasChantal CompèreKiyoyuki YanakataOlivier LorealJenny Le PersonHervé LhermiteJoël CharrierCatherine Boussard-PledelSatoru InoueKoji HyodoVirginie NazabalJulie KeirsseMarie-Laure AnneDue to the remarkable properties of chalcogenide (Chg) glasses, Chg optical waveguides should play a significant role in the development of optical biosensors. This paper describes the fabrication and properties of chalcogenide fibres and planar waveguides. Using optical fibre transparent in the mid-infrared spectral range we have developed a biosensor that can collect information on whole metabolism alterations, rapidly and in situ. Thanks to this sensor it is possible to collect infrared spectra by remote spectroscopy, by simple contact with the sample. In this way, we tried to determine spectral modifications due, on the one hand, to cerebral metabolism alterations caused by a transient focal ischemia in the rat brain and, in the other hand, starvation in the mouse liver. We also applied a microdialysis method, a well known technique for in vivo brain metabolism studies, as reference. In the field of integrated microsensors, reactive ion etching was used to pattern rib waveguides between 2 and 300 μm wide. This technique was used to fabricate Y optical junctions for optical interconnections on chalcogenide amorphous films, which can potentially increase the sensitivity and stability of an optical micro-sensor. The first tests were also carried out to functionalise the Chg planar waveguides with the aim of using them as (bio)sensors.http://www.mdpi.com/1424-8220/9/9/7398/chalcogenideoptical sensorfibreplanar waveguide |
| spellingShingle | Bruno Bureau Florent Colas Chantal Compère Kiyoyuki Yanakata Olivier Loreal Jenny Le Person Hervé Lhermite Joël Charrier Catherine Boussard-Pledel Satoru Inoue Koji Hyodo Virginie Nazabal Julie Keirsse Marie-Laure Anne Chalcogenide Glass Optical Waveguides for Infrared Biosensing Sensors chalcogenide optical sensor fibre planar waveguide |
| title | Chalcogenide Glass Optical Waveguides for Infrared Biosensing |
| title_full | Chalcogenide Glass Optical Waveguides for Infrared Biosensing |
| title_fullStr | Chalcogenide Glass Optical Waveguides for Infrared Biosensing |
| title_full_unstemmed | Chalcogenide Glass Optical Waveguides for Infrared Biosensing |
| title_short | Chalcogenide Glass Optical Waveguides for Infrared Biosensing |
| title_sort | chalcogenide glass optical waveguides for infrared biosensing |
| topic | chalcogenide optical sensor fibre planar waveguide |
| url | http://www.mdpi.com/1424-8220/9/9/7398/ |
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