Immunization with Tp0954, an adhesin of Treponema pallidum, provides protective efficacy in the rabbit model of experimental syphilis

Immunization with Tp0954, an adhesin of Treponema pallidum, provides protective efficacy in the rabbit model of experimental syphilis

Syphilis, a chronic multisystemic disease caused by spirochete Treponema pallidum subspecies pallidum infection, continues to be a serious global health problem and congenital syphilis remains a major cause of adverse outcomes in pregnancy in developing countries. The development of an effective vac...

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Bibliographic Details
Main Authors: Yuxing He, Dejun Chen, Yue Fu, Xinzhuo Huo, Feijun Zhao, Ling Yao, Xiuping Zhou, Pengfei Qi, Haoquan Yin, Longgu Cao, Hui Ling, Tiebing Zeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
Treponema pallidum
Tp0954
placental adhesin
vaccine
immunoprotection
dissemination
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1130593/full

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