Advances in the application of neuroinflammatory molecular imaging in brain malignancies
The prevalence of brain cancer has been increasing in recent decades, posing significant healthcare challenges. The introduction of immunotherapies has brought forth notable diagnostic imaging challenges for brain tumors. The tumor microenvironment undergoes substantial changes in induced immunosupp...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-07-01
|
| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1211900/full |
| _version_ | 1797777830528942080 |
|---|---|
| author | Wenxia Dong Ning Wang Zhe Qi |
| author_facet | Wenxia Dong Ning Wang Zhe Qi |
| author_sort | Wenxia Dong |
| collection | DOAJ |
| description | The prevalence of brain cancer has been increasing in recent decades, posing significant healthcare challenges. The introduction of immunotherapies has brought forth notable diagnostic imaging challenges for brain tumors. The tumor microenvironment undergoes substantial changes in induced immunosuppression and immune responses following the development of primary brain tumor and brain metastasis, affecting the progression and metastasis of brain tumors. Consequently, effective and accurate neuroimaging techniques are necessary for clinical practice and monitoring. However, patients with brain tumors might experience radiation-induced necrosis or other neuroinflammation. Currently, positron emission tomography and various magnetic resonance imaging techniques play a crucial role in diagnosing and evaluating brain tumors. Nevertheless, differentiating between brain tumors and necrotic lesions or inflamed tissues remains a significant challenge in the clinical diagnosis of the advancements in immunotherapeutics and precision oncology have underscored the importance of clinically applicable imaging measures for diagnosing and monitoring neuroinflammation. This review summarizes recent advances in neuroimaging methods aimed at enhancing the specificity of brain tumor diagnosis and evaluating inflamed lesions. |
| first_indexed | 2024-03-12T23:10:10Z |
| format | Article |
| id | doaj.art-fdb7e048532b4e148227eab5eac07651 |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-03-12T23:10:10Z |
| publishDate | 2023-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-fdb7e048532b4e148227eab5eac076512023-07-18T08:17:41ZengFrontiers Media S.A.Frontiers in Immunology1664-32242023-07-011410.3389/fimmu.2023.12119001211900Advances in the application of neuroinflammatory molecular imaging in brain malignanciesWenxia Dong0Ning Wang1Zhe Qi2Department of Radiology, The First People’s Hospital of Linping District, Hangzhou, ChinaDepartment of Medical Imaging, Jining Third People’s Hospital, Jining, Shandong, ChinaDepartment of Radiology, Zibo Central Hospital, Zibo, Shandong, ChinaThe prevalence of brain cancer has been increasing in recent decades, posing significant healthcare challenges. The introduction of immunotherapies has brought forth notable diagnostic imaging challenges for brain tumors. The tumor microenvironment undergoes substantial changes in induced immunosuppression and immune responses following the development of primary brain tumor and brain metastasis, affecting the progression and metastasis of brain tumors. Consequently, effective and accurate neuroimaging techniques are necessary for clinical practice and monitoring. However, patients with brain tumors might experience radiation-induced necrosis or other neuroinflammation. Currently, positron emission tomography and various magnetic resonance imaging techniques play a crucial role in diagnosing and evaluating brain tumors. Nevertheless, differentiating between brain tumors and necrotic lesions or inflamed tissues remains a significant challenge in the clinical diagnosis of the advancements in immunotherapeutics and precision oncology have underscored the importance of clinically applicable imaging measures for diagnosing and monitoring neuroinflammation. This review summarizes recent advances in neuroimaging methods aimed at enhancing the specificity of brain tumor diagnosis and evaluating inflamed lesions.https://www.frontiersin.org/articles/10.3389/fimmu.2023.1211900/fullmagnetic resonance imagingpositron emission tomographyneuroinflammationbrain tumormetastasis |
| spellingShingle | Wenxia Dong Ning Wang Zhe Qi Advances in the application of neuroinflammatory molecular imaging in brain malignancies Frontiers in Immunology magnetic resonance imaging positron emission tomography neuroinflammation brain tumor metastasis |
| title | Advances in the application of neuroinflammatory molecular imaging in brain malignancies |
| title_full | Advances in the application of neuroinflammatory molecular imaging in brain malignancies |
| title_fullStr | Advances in the application of neuroinflammatory molecular imaging in brain malignancies |
| title_full_unstemmed | Advances in the application of neuroinflammatory molecular imaging in brain malignancies |
| title_short | Advances in the application of neuroinflammatory molecular imaging in brain malignancies |
| title_sort | advances in the application of neuroinflammatory molecular imaging in brain malignancies |
| topic | magnetic resonance imaging positron emission tomography neuroinflammation brain tumor metastasis |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1211900/full |
| work_keys_str_mv | AT wenxiadong advancesintheapplicationofneuroinflammatorymolecularimaginginbrainmalignancies AT ningwang advancesintheapplicationofneuroinflammatorymolecularimaginginbrainmalignancies AT zheqi advancesintheapplicationofneuroinflammatorymolecularimaginginbrainmalignancies |