Anemoside A3 Inhibits Macrophage M2-Like Polarization to Prevent Triple-Negative Breast Cancer Metastasis

Anemoside A3 Inhibits Macrophage M2-Like Polarization to Prevent Triple-Negative Breast Cancer Metastasis

Triple negative breast cancer (TNBC) exhibits the characteristics of strong metastatic ability and a high recurrence rate, and M2-type macrophages play an important role in this process. Previous research data suggested that Anemoside A3 (A3), a monomeric component of Pulsatilla Chinensis, could pre...

Full description

Bibliographic Details
Main Authors:	Peng Liu, Yahui Liu, Lanying Chen, Zeping Fan, Yingying Luo, Yaru Cui
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Series:	Molecules
Subjects:	M2 polarization Anemoside A3 triple-negative breast cancer metastasis STAT3
Online Access:	https://www.mdpi.com/1420-3049/28/4/1611

Similar Items

Lentinan regulates the immune efficacy of macrophage for lung metastasis in triple negative breast
by: Ziyi Guan, et al.
Published: (2023-06-01)

Effects of Anemoside B4 on Plasma Metabolites in Cows with Clinical Mastitis
by: Liuhong Shen, et al.
Published: (2023-07-01)

Anemoside B4 Exerts Hypoglycemic Effect by Regulating the Expression of GLUT4 in HFD/STZ Rats
by: Qin Gong, et al.
Published: (2023-01-01)

Research progress on pharmacological actions and molecular mechanisms of Anemoside B4
by: Tianming Lu, et al.
Published: (2023-06-01)

Anemoside B4 attenuates RANKL-induced osteoclastogenesis by upregulating Nrf2 and dampens ovariectomy-induced bone loss
by: Zhen Cao, et al.
Published: (2023-11-01)

Effects of Anemoside B4 on Diarrhea Incidence, Serum Indices, and Fecal Microbial of Suckling Calves
by: Meng Lu, et al.
Published: (2022-04-01)

Electrospun multifunctional nanofibrous mats loaded with bioactive anemoside B4 for accelerated wound healing in diabetic mice
by: Hao Zhang, et al.
Published: (2022-12-01)

Anemoside B4 Inhibits Vascular Smooth Muscle Cell Proliferation, Migration, and Neointimal Hyperplasia
by: Dan Shan, et al.
Published: (2022-05-01)

LNK promotes the growth and metastasis of triple negative breast cancer via activating JAK/STAT3 and ERK1/2 pathway
by: Jianxin Lv, et al.
Published: (2020-04-01)

Anemoside B4 ameliorates TNBS-induced colitis through S100A9/MAPK/NF-κB signaling pathway
by: Yong Zhang, et al.
Published: (2021-01-01)

Osthole inhibits triple negative breast cancer cells by suppressing STAT3
by: Xuanxuan Dai, et al.
Published: (2018-12-01)

Eucannabinolide, a novel sesquiterpene lactone, suppresses the growth, metastasis and BCSCS-like traits of TNBC via inactivation of STAT3
by: Zhihui Zhu, et al.
Published: (2021-01-01)

SCAMP3 Regulates EGFR and Promotes Proliferation and Migration of Triple-Negative Breast Cancer Cells through the Modulation of AKT, ERK, and STAT3 Signaling Pathways
by: Ariana Acevedo-Díaz, et al.
Published: (2022-06-01)

Piperlongumine Induces Apoptosis and Synergizes with Doxorubicin by Inhibiting the JAK2-STAT3 Pathway in Triple-Negative Breast Cancer
by: Di Chen, et al.
Published: (2019-06-01)

Novel Galiellalactone Analogues Can Target STAT3 Phosphorylation and Cause Apoptosis in Triple-Negative Breast Cancer
by: Hyejin Ko, et al.
Published: (2019-05-01)

In Vitro and In Vivo Anti-Cancer Activity of Lasiokaurin in a Triple-Negative Breast Cancer Model
by: Jinrong Lin, et al.
Published: (2023-11-01)

Eupalinolide J Suppresses the Growth of Triple-Negative Breast Cancer Cells via Targeting STAT3 Signaling Pathway
by: Chenghua Lou, et al.
Published: (2019-09-01)

EGCG Inhibits Adipose-Derived Mesenchymal Stem Cells Differentiation into Adipocytes and Prevents a STAT3-Mediated Paracrine Oncogenic Control of Triple-Negative Breast Cancer Cell Invasive Phenotype
by: Narjara Gonzalez Suarez, et al.
Published: (2021-03-01)

Decarbromodiphenyl ether (BDE-209) exposure promotes migration of triple-negative breast cancer cells through STAT3 signaling pathway
by: XIE Shangfu, et al.
Published: (2023-09-01)

Stat3 Tyrosine 705 and Serine 727 Phosphorylation Associate With Clinicopathological Characteristics and Distinct Tumor Cell Phenotypes in Triple-Negative Breast Cancer
by: Michaela Stenckova, et al.
Published: (2022-08-01)

Reduced Expression of METTL3 Promotes Metastasis of Triple-Negative Breast Cancer by m6A Methylation-Mediated COL3A1 Up-Regulation
by: Yu Shi, et al.
Published: (2020-07-01)

SOX2 Promotes Cell Proliferation and Metastasis in Triple Negative Breast Cancer
by: Peng Liu, et al.
Published: (2018-08-01)

ALDH1A3 promotes invasion and metastasis in triple‐negative breast cancer by regulating the plasminogen activation pathway
by: Alamelu G. Bharadwaj, et al.
Published: (2024-01-01)

Elaeagnus angustifolia Plant Extract Induces Apoptosis via P53 and Signal Transducer and Activator of Transcription 3 Signaling Pathways in Triple-Negative Breast Cancer Cells
by: Arij Fouzat, et al.
Published: (2022-03-01)

Oncolytic adenovirus encoding apolipoprotein A1 suppresses metastasis of triple-negative breast cancer in mice
by: Jie Dong, et al.
Published: (2024-04-01)

Sanyin Formula Enhances the Therapeutic Efficacy of Paclitaxel in Triple-Negative Breast Cancer Metastases through the JAK/STAT3 Pathway in Mice
by: Chunyu Wu, et al.
Published: (2022-12-01)

Functional and genomic characterisation of a xenograft model system for the study of metastasis in triple-negative breast cancer
by: Cameron N. Johnstone, et al.
Published: (2018-05-01)

Anemoside B4 protects against Klebsiella pneumoniae- and influenza virus FM1-induced pneumonia via the TLR4/Myd88 signaling pathway in mice
by: Jia He, et al.
Published: (2020-07-01)

Modeling Tumor: Lymphatic Interactions in Lymphatic Metastasis of Triple Negative Breast Cancer
by: Kyungmin Ji, et al.
Published: (2021-11-01)

Carnosol, a Natural Polyphenol, Inhibits Migration, Metastasis, and Tumor Growth of Breast Cancer via a ROS-Dependent Proteasome Degradation of STAT3
by: Halima Alsamri, et al.
Published: (2019-08-01)

A prognostic model for triple-negative breast cancer patients with liver metastasis: A population-based study
by: Liguo Zhang, et al.
Published: (2024-04-01)

Effects of Cancer Stem Cells in Triple-Negative Breast Cancer and Brain Metastasis: Challenges and Solutions
by: Kha-Liang Lee, et al.
Published: (2020-07-01)

Corrigendum: Carnosol, a natural polyphenol, inhibits migration, metastasis, and tumor growth of breast cancer via a ROS-dependent proteasome degradation of STAT3
by: Halima Alsamri, et al.
Published: (2024-02-01)

Molecular Mechanisms and Emerging Therapeutic Targets of Triple-Negative Breast Cancer Metastasis
by: Christiana Neophytou, et al.
Published: (2018-02-01)

C/EBPβ regulates the JAK/STAT signaling pathway in triple‐negative breast cancer
by: Shu Wang, et al.
Published: (2021-04-01)

circAR-E2E4-miR-665-STAT3 axis is a potential regulatory network in triple-negative breast cancer
by: Hao Xu, et al.
Published: (2023-01-01)

Bioinformatic analysis of drug targets for triple-negative breast cancer
by: Xiao-Wei Li, et al.
Published: (2023-02-01)

HMGA2 Supports Cancer Hallmarks in Triple-Negative Breast Cancer
by: Behzad Mansoori, et al.
Published: (2021-10-01)

The Effect of Salvianolic Acid A on Tumor-Associated Macrophage Polarization and Its Mechanisms in the Tumor Microenvironment of Triple-Negative Breast Cancer
by: Chao Tang, et al.
Published: (2024-03-01)

Prognosis prediction and risk factors for triple‐negative breast cancer patients with brain metastasis: A population‐based study
by: Yuqin Yang, et al.
Published: (2023-04-01)