Anti-photoaging effect and mechanism of flexible liposomes co-loaded with apigenin and doxycycline

Anti-photoaging effect and mechanism of flexible liposomes co-loaded with apigenin and doxycycline

Prolonged exposure to UV light can lead to photo-ageing of the skin. Therefore, the development and application of anti-photoaging drugs is urgent. In this study, we co-loaded apigenin (Apn) and doxycycline (Doc), a broad-spectrum inhibitor of matrix metalloproteinases (MMPs), into flexible liposome...

Full description

Bibliographic Details
Main Authors:	Chang Liu, Xiao Guo, Yutong Chen, Meijun Zhao, Shuai Shi, Zheng Luo, Jian Song, Zhihong Zhang, Wenchuang Yang, Keyi Liu
Format:	Article
Language:	English
Published:	Elsevier 2023-08-01
Series:	Biomedicine & Pharmacotherapy
Subjects:	Apigenin Doxycycline Flexible liposomes Photoaging Matrix metalloproteinases
Online Access:	http://www.sciencedirect.com/science/article/pii/S0753332223007886

Similar Items

Preparation and Evaluation of Liposomes and Niosomes Containing Total Ginsenosides for Anti-Photoaging Therapy
by: Yuanyuan Jin, et al.
Published: (2022-04-01)

Role of doxycycline to resolve different types of non-malignant lung and pleural pathology: The results of a pilot observation
by: Parthasarathi Bhattacharyya, et al.
Published: (2015-01-01)

Effects of Topical Intranasal Doxycycline Treatment in the Rat Allergic Rhinitis Model
by: Mehmet Ozgür Avincsal, et al.
Published: (2014-06-01)

Doxycycline inhibits matrix metalloproteinase-9 and laminin degradation after transient global cerebral ischemia
by: Hyung Lee, et al.
Published: (2009-05-01)

The Effect of Doxycycline on Achilles Tendon Repair in a Rat Model
by: Sobhani-Eraghi A, et al.
Published: (2020-11-01)

Anti-inflammatory and Anti-apoptotic Effect of Valproic Acid and Doxycycline Independent from MMP Inhibition in Early Radiation Damage
by: Ferda Hoşgörler, et al.
Published: (2016-10-01)

In silico study of Impatiens balsamina L. for the screening of bioactive compounds as novel matrix metalloproteinase-1 inhibitor against photoaging
by: Sindi Fujiyanti, et al.
Published: (2023-09-01)

Synergistic apoptotic effects of apigenin TPGS liposomes and tyroservatide: implications for effective treatment of lung cancer
by: Jin X, et al.
Published: (2017-07-01)

Effect of Doxycycline Microencapsulation on Buccal Films: Stability, Mucoadhesion and In Vitro Drug Release
by: Venu Gopal Reddy Patlolla, et al.
Published: (2021-04-01)

D-α-tocopherol polyethylene glycol succinate and Poloxamer 188 modified liposomal chrysin hydrogel for enhanced topical treatment of ultraviolet-induced skin photoaging damage
by: Xiang Wang, et al.
Published: (2023-07-01)

Chlorin E6-Curcumin-Mediated Photodynamic Therapy Promotes an Anti-Photoaging Effect in UVB-Irradiated Fibroblasts
by: Til Bahadur Thapa Magar, et al.
Published: (2023-08-01)

Anti-photoaging and Photoprotective Compounds Derived from Marine Organisms
by: Ramjee Pallela, et al.
Published: (2010-04-01)

Chlorogenic Acid Prevents UVA-Induced Skin Photoaging through Regulating Collagen Metabolism and Apoptosis in Human Dermal Fibroblasts
by: Nina Xue, et al.
Published: (2022-06-01)

The flavonoid hesperidin exerts anti-photoaging effect by downregulating matrix metalloproteinase (MMP)-9 expression via mitogen activated protein kinase (MAPK)-dependent signaling pathways
by: Hee Jeong Lee, et al.
Published: (2018-01-01)

The Mechanism of Peach Gum Polysaccharide Preventing UVB-Induced Skin Photoaging by Regulating Matrix Metalloproteinanse and Oxidative Factors
by: Min Yang, et al.
Published: (2023-05-01)

Boosting the Photoaged Skin: The Potential Role of Dietary Components
by: Ruixuan Geng, et al.
Published: (2021-05-01)

Doxiciclina em pacientes com linfangioleiomiomatose: segurança e eficácia no bloqueio de metaloproteinases Doxycycline use in patients with lymphangioleiomyomatosis: safety and efficacy in metalloproteinase blockade
by: Suzana Pinheiro Pimenta, et al.
Published: (2011-08-01)

Can long term add-on doxycycline improve lung function in asthma: The result of an open prospective real-world observation
by: Parthasarathi Bhattacharyya, et al.
Published: (2023-01-01)

Isolation and purification of Eleutherococcus sessiliflorus (Rupr. & Maxim.) S. Y. Hu peptides and study of their antioxidant effects and mechanisms
by: Chang Liu, et al.
Published: (2024-02-01)

Matrix Metalloproteinases Inhibition by Doxycycline Rescues Extracellular Matrix Organization and Partly Reverts Myofibroblast Differentiation in Hypermobile Ehlers-Danlos Syndrome Dermal Fibroblasts: A Potential Therapeutic Target?
by: Nicola Chiarelli, et al.
Published: (2021-11-01)

Low-dose doxycycline prevents inflammatory bone resorption in rats
by: M.M. Bezerra, et al.
Published: (2002-05-01)

Advances in the Applications of Extracellular Vesicle for the Treatment of Skin Photoaging: A Comprehensive Review
by: Cai CS, et al.
Published: (2023-11-01)

Effect of doxycycline in patients of moderate to severe chronic obstructive pulmonary disease with stable symptoms
by: Prashant S Dalvi, et al.
Published: (2011-01-01)

Alterations in extracellular matrix composition during aging and photoaging of the skin
by: Maxwell C. McCabe, et al.
Published: (2020-11-01)

Phosphatidylserine prevents UV-induced decrease of type I procollagen and increase of MMP-1 in dermal fibroblasts and human skin in vivo
by: Soyun Cho, et al.
Published: (2008-06-01)

Role of matrix metalloproteinase in the aneurismatic aortic disease
by: Nicola Troisi, et al.
Published: (2004-09-01)

Doxycycline-Induced Changes in Circulating MMP or TIMP2 Levels Are Not Associated with Skeletal-Related Event-Free or Overall Survival in Patients with Bone Metastases from Breast Cancer
by: Huijun Zhao, et al.
Published: (2023-01-01)

Protocatechuic Aldehyde Attenuates UVA-induced Photoaging in Human Dermal Fibroblast Cells by Suppressing MAPKs/AP-1 and NF-κB Signaling Pathways
by: Yuling Ding, et al.
Published: (2020-06-01)

An alternative therapy for idiopathic pulmonary fibrosis by doxycycline through matrix metalloproteinase inhibition
by: Amartya Mishra, et al.
Published: (2011-01-01)

Anti-Photoaging Effect of Plant Extract Fermented with <i>Lactobacillus buchneri</i> on CCD-986sk Fibroblasts and HaCaT Keratinocytes
by: Yun-Mi Kang, et al.
Published: (2020-01-01)

Protective effects of Zingiber cassumunar Roxb. extract against UVB‐induced oxidative stress in Wistar albino rats (Rattus novergicus Berkenhout, 1769)
by: Dian Ayuning Tyas, et al.
Published: (2024-03-01)

Evaluation of caffeine as inhibitor against collagenase, elastase and tyrosinase using in silico and in vitro approach
by: Kyung Eun Lee, et al.
Published: (2019-01-01)

Sunscreens as a prevention of the photoaging
by: Paulina Kostrzewska, et al.
Published: (2020-07-01)

Marine Bioactive Peptides: Anti-Photoaging Mechanisms and Potential Skin Protective Effects
by: Xiaoliang Zhang, et al.
Published: (2024-01-01)

The Efficacy of Topical Vitamin C and Microneedling for Photoaging
by: Karina Dyahtantri Pratiwi, et al.
Published: (2021-03-01)

Matrix Metalloproteinases as Biomarkers of Atherosclerotic Plaque Instability
by: Wioletta Olejarz, et al.
Published: (2020-05-01)

Proof of Concept: Matrix metalloproteinase inhibitor decreases inflammation and improves muscle insulin sensitivity in people with type 2 diabetes
by: Frankwich Karen, et al.
Published: (2012-10-01)

Tetracyclines increase lipid phosphate phosphatase expression on plasma membranes and turnover of plasma lysophosphatidate[S]
by: Xiaoyun Tang, et al.
Published: (2016-04-01)

Adjunctive Subantimicrobial Dose Doxycycline in the Treatment of Chronic Periodontitis in Type 2 Diabetic Patients: A Unique Combination Therapy
by: Gomaa Marwa Abdelhakim, et al.
Published: (2018-03-01)

Pinus densiflora extract protects human skin fibroblasts against UVB-induced photoaging by inhibiting the expression of MMPs and increasing type I procollagen expression
by: Hoe-Yune Jung, et al.
Published: (2014-01-01)