Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) Diagnosis of Recurrent Anal Cancer after Chemoradiation and Negative Forceps Biopsies: A Case Report
A 69-year-old woman with a history of uT2 N0 post-treated anal squamous cell cancer (SCC) presented for EUS for perianal pain. Two months prior, a digital rectal examination was significant for an indurated lesion on the left lateral rectal wall just proximal to the dentate line. A sigmoidoscopy rev...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2009-01-01
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| Series: | Clinical Medicine Insights: Oncology |
| Online Access: | https://doi.org/10.4137/CMO.S993 |
| _version_ | 1818495709062627328 |
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| author | Julia Leblanc Pradermchai Kongkam |
| author_facet | Julia Leblanc Pradermchai Kongkam |
| author_sort | Julia Leblanc |
| collection | DOAJ |
| description | A 69-year-old woman with a history of uT2 N0 post-treated anal squamous cell cancer (SCC) presented for EUS for perianal pain. Two months prior, a digital rectal examination was significant for an indurated lesion on the left lateral rectal wall just proximal to the dentate line. A sigmoidoscopy revealed mild narrowing of the anal canal and an ulcerated friable mucosa in the same area. A biopsy demonstrated ulceration without malignancy. EUS showed a hypoechoic, non-circumferential, left-sided distal rectal mass. EUS-FNA was performed. Cytology demonstrated poorly differentiated SCC. This was confirmed by subsequent surgical resection. While endoscopic biopsy of suspected anal recurrences is usually sufficient, histologic or cytologic confirmation are necessary, as radiation-induced changes are difficult to differentiate from tumor recurrence. This case demonstrates that EUS-FNA is useful in surveillance of anal SCC when there is a high clinical suspicion of recurrence. |
| first_indexed | 2024-12-10T18:24:21Z |
| format | Article |
| id | doaj.art-fdbb88c2b9e64005b8ccbd8283b3c0f4 |
| institution | Directory Open Access Journal |
| issn | 1179-5549 |
| language | English |
| last_indexed | 2024-12-10T18:24:21Z |
| publishDate | 2009-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Clinical Medicine Insights: Oncology |
| spelling | doaj.art-fdbb88c2b9e64005b8ccbd8283b3c0f42022-12-22T01:38:07ZengSAGE PublishingClinical Medicine Insights: Oncology1179-55492009-01-01310.4137/CMO.S993Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) Diagnosis of Recurrent Anal Cancer after Chemoradiation and Negative Forceps Biopsies: A Case ReportJulia Leblanc0Pradermchai Kongkam1Indiana University Medical Center, Division of Gastroenterology and Hepatology.Indiana University Medical Center, Division of Gastroenterology and Hepatology.A 69-year-old woman with a history of uT2 N0 post-treated anal squamous cell cancer (SCC) presented for EUS for perianal pain. Two months prior, a digital rectal examination was significant for an indurated lesion on the left lateral rectal wall just proximal to the dentate line. A sigmoidoscopy revealed mild narrowing of the anal canal and an ulcerated friable mucosa in the same area. A biopsy demonstrated ulceration without malignancy. EUS showed a hypoechoic, non-circumferential, left-sided distal rectal mass. EUS-FNA was performed. Cytology demonstrated poorly differentiated SCC. This was confirmed by subsequent surgical resection. While endoscopic biopsy of suspected anal recurrences is usually sufficient, histologic or cytologic confirmation are necessary, as radiation-induced changes are difficult to differentiate from tumor recurrence. This case demonstrates that EUS-FNA is useful in surveillance of anal SCC when there is a high clinical suspicion of recurrence.https://doi.org/10.4137/CMO.S993 |
| spellingShingle | Julia Leblanc Pradermchai Kongkam Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) Diagnosis of Recurrent Anal Cancer after Chemoradiation and Negative Forceps Biopsies: A Case Report Clinical Medicine Insights: Oncology |
| title | Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) Diagnosis of Recurrent Anal Cancer after Chemoradiation and Negative Forceps Biopsies: A Case Report |
| title_full | Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) Diagnosis of Recurrent Anal Cancer after Chemoradiation and Negative Forceps Biopsies: A Case Report |
| title_fullStr | Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) Diagnosis of Recurrent Anal Cancer after Chemoradiation and Negative Forceps Biopsies: A Case Report |
| title_full_unstemmed | Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) Diagnosis of Recurrent Anal Cancer after Chemoradiation and Negative Forceps Biopsies: A Case Report |
| title_short | Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) Diagnosis of Recurrent Anal Cancer after Chemoradiation and Negative Forceps Biopsies: A Case Report |
| title_sort | endoscopic ultrasound guided fine needle aspiration eus fna diagnosis of recurrent anal cancer after chemoradiation and negative forceps biopsies a case report |
| url | https://doi.org/10.4137/CMO.S993 |
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