Rapid green synthesis of silver nanoparticles and evaluation of their properties for oral disease therapy
A rapid, cost-efficient, and eco-friendly method for synthesis of silver nanoparticles (AgNPs) was developed using an herb extract (Glycyrrhiza glabra root) as a reducing agent and a kitchen microwave as a reaction accelerator. A solution of dark brown appeared and was examined by UV-visible spect...
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| Format: | Article |
| Language: | English |
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Prince of Songkla University
2018-08-01
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| Series: | Songklanakarin Journal of Science and Technology (SJST) |
| Subjects: | |
| Online Access: | https://rdo.psu.ac.th/sjstweb/journal/40-4/14.pdf |
| _version_ | 1811283475075956736 |
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| author | Suttipalin Suwannakul Sirorat Wacharanad Plykaeow Chaibenjawong |
| author_facet | Suttipalin Suwannakul Sirorat Wacharanad Plykaeow Chaibenjawong |
| author_sort | Suttipalin Suwannakul |
| collection | DOAJ |
| description | A rapid, cost-efficient, and eco-friendly method for synthesis of silver nanoparticles (AgNPs) was developed using an
herb extract (Glycyrrhiza glabra root) as a reducing agent and a kitchen microwave as a reaction accelerator. A solution of dark
brown appeared and was examined by UV-visible spectroscopy. Scanning and transmission electron microscopes as well as an
atomic force microscope were used to confirm their physical nature. The AgNPs revealed feasibility for treatment of oral
diseases. Their antimicrobial activities against Streptococcus mutans were indicated with minimal inhibitory and minimal
bactericidal concentrations of 6.25 and 25 μg/ml, respectively. They showed toxicity to cancer cell lines (HN-30) but had no
effect on human gingival fibroblasts. Anti-oxidative activity was also observed which suggested potential in medical
applications. |
| first_indexed | 2024-04-13T02:13:17Z |
| format | Article |
| id | doaj.art-fdbc0d2da689407f8801997399620ff7 |
| institution | Directory Open Access Journal |
| issn | 0125-3395 |
| language | English |
| last_indexed | 2024-04-13T02:13:17Z |
| publishDate | 2018-08-01 |
| publisher | Prince of Songkla University |
| record_format | Article |
| series | Songklanakarin Journal of Science and Technology (SJST) |
| spelling | doaj.art-fdbc0d2da689407f8801997399620ff72022-12-22T03:07:15ZengPrince of Songkla UniversitySongklanakarin Journal of Science and Technology (SJST)0125-33952018-08-0140483183910.14456/sjst-psu.2018.112Rapid green synthesis of silver nanoparticles and evaluation of their properties for oral disease therapySuttipalin Suwannakul0Sirorat Wacharanad1Plykaeow Chaibenjawong2Division of Periodontology, Department of Preventive Dentistry, Faculty of Dentistry, Naresuan University, Mueang, Phitsanulok, 65000 ThailandDivision of Periodontology, Department of Preventive Dentistry, Faculty of Dentistry, Naresuan University, Mueang, Phitsanulok, 65000 ThailandDepartment of Microbiology and Parasitology, Faculty of Medical Science, Naresuan University, Mueang, Phitsanulok, 65000 ThailandA rapid, cost-efficient, and eco-friendly method for synthesis of silver nanoparticles (AgNPs) was developed using an herb extract (Glycyrrhiza glabra root) as a reducing agent and a kitchen microwave as a reaction accelerator. A solution of dark brown appeared and was examined by UV-visible spectroscopy. Scanning and transmission electron microscopes as well as an atomic force microscope were used to confirm their physical nature. The AgNPs revealed feasibility for treatment of oral diseases. Their antimicrobial activities against Streptococcus mutans were indicated with minimal inhibitory and minimal bactericidal concentrations of 6.25 and 25 μg/ml, respectively. They showed toxicity to cancer cell lines (HN-30) but had no effect on human gingival fibroblasts. Anti-oxidative activity was also observed which suggested potential in medical applications.https://rdo.psu.ac.th/sjstweb/journal/40-4/14.pdfsilver nanoparticlesGlycyrrhiza glabraStreptococcus mutansantimicrobialcytotoxicityanti-oxidative |
| spellingShingle | Suttipalin Suwannakul Sirorat Wacharanad Plykaeow Chaibenjawong Rapid green synthesis of silver nanoparticles and evaluation of their properties for oral disease therapy Songklanakarin Journal of Science and Technology (SJST) silver nanoparticles Glycyrrhiza glabra Streptococcus mutans antimicrobial cytotoxicity anti-oxidative |
| title | Rapid green synthesis of silver nanoparticles and evaluation of their properties for oral disease therapy |
| title_full | Rapid green synthesis of silver nanoparticles and evaluation of their properties for oral disease therapy |
| title_fullStr | Rapid green synthesis of silver nanoparticles and evaluation of their properties for oral disease therapy |
| title_full_unstemmed | Rapid green synthesis of silver nanoparticles and evaluation of their properties for oral disease therapy |
| title_short | Rapid green synthesis of silver nanoparticles and evaluation of their properties for oral disease therapy |
| title_sort | rapid green synthesis of silver nanoparticles and evaluation of their properties for oral disease therapy |
| topic | silver nanoparticles Glycyrrhiza glabra Streptococcus mutans antimicrobial cytotoxicity anti-oxidative |
| url | https://rdo.psu.ac.th/sjstweb/journal/40-4/14.pdf |
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