Magnetically controlled capsule endoscopy in one-time gastro-small intestinal joint examination: a two-centre experience
Abstract Background The lesions of certain diseases are widely distributed in both stomach and small intestine, while the step-by-step strategy of gastroscopy followed by enteroscopy can be burdensome and costly. We aimed to determine if magnetically controlled capsule endoscopy (MCE) could be used...
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| Format: | Article |
| Language: | English |
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BMC
2022-05-01
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| Series: | BMC Gastroenterology |
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| Online Access: | https://doi.org/10.1186/s12876-022-02302-0 |
| _version_ | 1811305862356008960 |
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| author | Ya-Wei Liu Yuan-Chen Wang Jia-Hui Zhu Xi Jiang Wei Zhou Jie Zhang Zhuan Liao En-Qiang Linghu |
| author_facet | Ya-Wei Liu Yuan-Chen Wang Jia-Hui Zhu Xi Jiang Wei Zhou Jie Zhang Zhuan Liao En-Qiang Linghu |
| author_sort | Ya-Wei Liu |
| collection | DOAJ |
| description | Abstract Background The lesions of certain diseases are widely distributed in both stomach and small intestine, while the step-by-step strategy of gastroscopy followed by enteroscopy can be burdensome and costly. We aimed to determine if magnetically controlled capsule endoscopy (MCE) could be used in one-time gastro-small intestine (GSI) joint examination. Methods In this study, data of patients in Chinese PLA General Hospital and Changhai Hospital who underwent MCE GSI examination from January 2020 to August 2021 were retrospectively analysed. The primary outcome of this study was the success rate of one-time GSI joint examination, and secondary outcomes included visualization and cleanliness of gastrointestinal tract, gastrointestinal transit times, diagnostic yield and safety of MCE examination. Results A total of 768 patients were included. The success rate of one-time GSI joint examination was 92.58%. There were 94.92% MCEs observed > 90% gastric mucosa in the 6 anatomic landmarks. The rate of complete small bowel examination was 97.40%. The median gastric examination time, gastric transit time and small intestine transit time were 8.18 min, 63.89 min and 4.89 h, respectively. Magnetic steering of MCE significantly decreased gastric transit time (8.92 min vs. 79.68 min, P = 0.001) and increased duodenal lesion detection rate (13.47% vs. 6.26%, P = 0.001) when compared with non-magnetic steering group. Two capsules were retained and were removed by enteroscopy or spontaneously excreted. Conclusions MCE is feasible to complete GSI joint examination and the detection of both gastric and small intestinal diseases can be achieved simultaneously. Trial registration Clinical Trial Registration ClinicalTrials.gov, ID: NCT05069233. |
| first_indexed | 2024-04-13T08:34:03Z |
| format | Article |
| id | doaj.art-fdbcf13386a24dcb91431ec08d9d0cf7 |
| institution | Directory Open Access Journal |
| issn | 1471-230X |
| language | English |
| last_indexed | 2024-04-13T08:34:03Z |
| publishDate | 2022-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Gastroenterology |
| spelling | doaj.art-fdbcf13386a24dcb91431ec08d9d0cf72022-12-22T02:54:10ZengBMCBMC Gastroenterology1471-230X2022-05-012211910.1186/s12876-022-02302-0Magnetically controlled capsule endoscopy in one-time gastro-small intestinal joint examination: a two-centre experienceYa-Wei Liu0Yuan-Chen Wang1Jia-Hui Zhu2Xi Jiang3Wei Zhou4Jie Zhang5Zhuan Liao6En-Qiang Linghu7Department of Gastroenterology, The First Medical Center of Chinese PLA General Hospital/Chinese PLA Postgraduate Military Medical SchoolNational Clinical Research Center for Digestive Diseases, Department of Gastroenterology, Changhai HospitalNational Clinical Research Center for Digestive Diseases, Department of Gastroenterology, Changhai HospitalNational Clinical Research Center for Digestive Diseases, Department of Gastroenterology, Changhai HospitalNational Clinical Research Center for Digestive Diseases, Department of Gastroenterology, Changhai HospitalDepartment of Gastroenterology, The First Medical Center of Chinese PLA General Hospital/Chinese PLA Postgraduate Military Medical SchoolNational Clinical Research Center for Digestive Diseases, Department of Gastroenterology, Changhai HospitalDepartment of Gastroenterology, The First Medical Center of Chinese PLA General Hospital/Chinese PLA Postgraduate Military Medical SchoolAbstract Background The lesions of certain diseases are widely distributed in both stomach and small intestine, while the step-by-step strategy of gastroscopy followed by enteroscopy can be burdensome and costly. We aimed to determine if magnetically controlled capsule endoscopy (MCE) could be used in one-time gastro-small intestine (GSI) joint examination. Methods In this study, data of patients in Chinese PLA General Hospital and Changhai Hospital who underwent MCE GSI examination from January 2020 to August 2021 were retrospectively analysed. The primary outcome of this study was the success rate of one-time GSI joint examination, and secondary outcomes included visualization and cleanliness of gastrointestinal tract, gastrointestinal transit times, diagnostic yield and safety of MCE examination. Results A total of 768 patients were included. The success rate of one-time GSI joint examination was 92.58%. There were 94.92% MCEs observed > 90% gastric mucosa in the 6 anatomic landmarks. The rate of complete small bowel examination was 97.40%. The median gastric examination time, gastric transit time and small intestine transit time were 8.18 min, 63.89 min and 4.89 h, respectively. Magnetic steering of MCE significantly decreased gastric transit time (8.92 min vs. 79.68 min, P = 0.001) and increased duodenal lesion detection rate (13.47% vs. 6.26%, P = 0.001) when compared with non-magnetic steering group. Two capsules were retained and were removed by enteroscopy or spontaneously excreted. Conclusions MCE is feasible to complete GSI joint examination and the detection of both gastric and small intestinal diseases can be achieved simultaneously. Trial registration Clinical Trial Registration ClinicalTrials.gov, ID: NCT05069233.https://doi.org/10.1186/s12876-022-02302-0Magnetically controlled capsule endoscopyGastricSmall intestineJoint examination |
| spellingShingle | Ya-Wei Liu Yuan-Chen Wang Jia-Hui Zhu Xi Jiang Wei Zhou Jie Zhang Zhuan Liao En-Qiang Linghu Magnetically controlled capsule endoscopy in one-time gastro-small intestinal joint examination: a two-centre experience BMC Gastroenterology Magnetically controlled capsule endoscopy Gastric Small intestine Joint examination |
| title | Magnetically controlled capsule endoscopy in one-time gastro-small intestinal joint examination: a two-centre experience |
| title_full | Magnetically controlled capsule endoscopy in one-time gastro-small intestinal joint examination: a two-centre experience |
| title_fullStr | Magnetically controlled capsule endoscopy in one-time gastro-small intestinal joint examination: a two-centre experience |
| title_full_unstemmed | Magnetically controlled capsule endoscopy in one-time gastro-small intestinal joint examination: a two-centre experience |
| title_short | Magnetically controlled capsule endoscopy in one-time gastro-small intestinal joint examination: a two-centre experience |
| title_sort | magnetically controlled capsule endoscopy in one time gastro small intestinal joint examination a two centre experience |
| topic | Magnetically controlled capsule endoscopy Gastric Small intestine Joint examination |
| url | https://doi.org/10.1186/s12876-022-02302-0 |
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