Dynamic 18F-FDopa PET Imaging for Newly Diagnosed Gliomas: Is a Semiquantitative Model Sufficient?

Dynamic 18F-FDopa PET Imaging for Newly Diagnosed Gliomas: Is a Semiquantitative Model Sufficient?

PurposeDynamic amino acid positron emission tomography (PET) has become essential in neuro-oncology, most notably for its prognostic value in the noninvasive prediction of isocitrate dehydrogenase (IDH) mutations in newly diagnosed gliomas. The 6-[18F]fluoro-l-DOPA (18F-FDOPA) kinetic model has an u...

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Bibliographic Details
Main Authors: Timothée Zaragori, Matthieu Doyen, Fabien Rech, Marie Blonski, Luc Taillandier, Laëtitia Imbert, Antoine Verger
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Oncology
Subjects:
DOPA
PET
compartmental modeling
dynamic analysis
glioma
IDH mutation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.735257/full

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