Colistin potentiation in multidrug-resistant Acinetobacter baumannii by a non-cytotoxic guanidine derivative of silver

Colistin potentiation in multidrug-resistant Acinetobacter baumannii by a non-cytotoxic guanidine derivative of silver

A novel nano-formulation (NF) that sensitizes Acinetobacter baumannii (AB) to otherwise ineffective colistin is described in the present study. Infections due to multidrug resistant (MDR) AB represent a major therapeutic challenge, especially in situations of pre-existing colistin resistance (colR)....

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Bibliographic Details
Main Authors: Deepak Kumar, Chaitali Singhal, Manisha Yadav, Pooja Joshi, Priyanka Patra, Subhash Tanwar, Amitava Das, Sumit Kumar Pramanik, Susmita Chaudhuri
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Microbiology
Subjects:
colistin resistance
Acinetobacter baumannii
antibiotic
potentiators
nano-formulation
silver
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1006604/full

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