Madelung’s disease and pulmonary aspergillosis: a case report and literature review
Abstract Background Madelung’s disease (MD) is a rare disorder of fat metabolism, which is usually associated with diabetes, hyperuricemia, liver disease, nevertheless there is no report of a patient with MD and pulmonary aspergillosis (PA). This article aimed to enhance the awareness of this two di...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2020-05-01
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| Series: | Journal of Cardiothoracic Surgery |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13019-020-01166-3 |
| _version_ | 1819064975595929600 |
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| author | Weijiang Ma Xilong Zhao Xu Li Chenxi Zang Limin Yang Yan Wang Xin Liu |
| author_facet | Weijiang Ma Xilong Zhao Xu Li Chenxi Zang Limin Yang Yan Wang Xin Liu |
| author_sort | Weijiang Ma |
| collection | DOAJ |
| description | Abstract Background Madelung’s disease (MD) is a rare disorder of fat metabolism, which is usually associated with diabetes, hyperuricemia, liver disease, nevertheless there is no report of a patient with MD and pulmonary aspergillosis (PA). This article aimed to enhance the awareness of this two diseases and discuss the possible mechanism of the combination of them preliminarily. Case presentation In this case, we described a 56-year-old male patient with cough, expectoration and dyspnea. His neck has a very peculiar appearance. Chest enhanced CT scan showed there were multiple nodules in both lungs, some of which had cavities and the mediastinal lymph nodes were swollen. Ultrasound scan of the neck showed diffuse hyperplasia of subcutaneous fat in neck and bilateral supraclavicular fossa. Fortunately, after performing pulmonary wedge resection aimed at pathological examination and giving relevant treatments, this patient was finally diagnosed as MD with PA, and his symptoms were significantly relieved. Conclusions MD is rare, the phenomenon that MD combined with PA is rarer. Immune disorder may be the possible mechanism. |
| first_indexed | 2024-12-21T15:39:07Z |
| format | Article |
| id | doaj.art-fdc733535d5841e58c8e0cce8a644e74 |
| institution | Directory Open Access Journal |
| issn | 1749-8090 |
| language | English |
| last_indexed | 2024-12-21T15:39:07Z |
| publishDate | 2020-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Cardiothoracic Surgery |
| spelling | doaj.art-fdc733535d5841e58c8e0cce8a644e742022-12-21T18:58:34ZengBMCJournal of Cardiothoracic Surgery1749-80902020-05-011511610.1186/s13019-020-01166-3Madelung’s disease and pulmonary aspergillosis: a case report and literature reviewWeijiang Ma0Xilong Zhao1Xu Li2Chenxi Zang3Limin Yang4Yan Wang5Xin Liu6Department of Thoracic Surgery, Second Affiliated Hospital of Kunming Medical UniversityDepartment of Pathology, 920th Hospital of Joint Logistics Support Force of Chinese People’s Liberation ArmyDepartment of Thoracic Surgery, Second Affiliated Hospital of Kunming Medical UniversityDepartment of Thoracic Surgery, Second Affiliated Hospital of Kunming Medical UniversityDepartment of Thoracic Surgery, Second Affiliated Hospital of Kunming Medical UniversityDepartment of Pathology, Second Affiliated Hospital of Kunming Medical UniversityDepartment of Thoracic Surgery, Second Affiliated Hospital of Kunming Medical UniversityAbstract Background Madelung’s disease (MD) is a rare disorder of fat metabolism, which is usually associated with diabetes, hyperuricemia, liver disease, nevertheless there is no report of a patient with MD and pulmonary aspergillosis (PA). This article aimed to enhance the awareness of this two diseases and discuss the possible mechanism of the combination of them preliminarily. Case presentation In this case, we described a 56-year-old male patient with cough, expectoration and dyspnea. His neck has a very peculiar appearance. Chest enhanced CT scan showed there were multiple nodules in both lungs, some of which had cavities and the mediastinal lymph nodes were swollen. Ultrasound scan of the neck showed diffuse hyperplasia of subcutaneous fat in neck and bilateral supraclavicular fossa. Fortunately, after performing pulmonary wedge resection aimed at pathological examination and giving relevant treatments, this patient was finally diagnosed as MD with PA, and his symptoms were significantly relieved. Conclusions MD is rare, the phenomenon that MD combined with PA is rarer. Immune disorder may be the possible mechanism.http://link.springer.com/article/10.1186/s13019-020-01166-3Madelung’s diseasePulmonary aspergillosisOpportunistic pathogenImmune disorder |
| spellingShingle | Weijiang Ma Xilong Zhao Xu Li Chenxi Zang Limin Yang Yan Wang Xin Liu Madelung’s disease and pulmonary aspergillosis: a case report and literature review Journal of Cardiothoracic Surgery Madelung’s disease Pulmonary aspergillosis Opportunistic pathogen Immune disorder |
| title | Madelung’s disease and pulmonary aspergillosis: a case report and literature review |
| title_full | Madelung’s disease and pulmonary aspergillosis: a case report and literature review |
| title_fullStr | Madelung’s disease and pulmonary aspergillosis: a case report and literature review |
| title_full_unstemmed | Madelung’s disease and pulmonary aspergillosis: a case report and literature review |
| title_short | Madelung’s disease and pulmonary aspergillosis: a case report and literature review |
| title_sort | madelung s disease and pulmonary aspergillosis a case report and literature review |
| topic | Madelung’s disease Pulmonary aspergillosis Opportunistic pathogen Immune disorder |
| url | http://link.springer.com/article/10.1186/s13019-020-01166-3 |
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