Drug interactions of non-vitamin K antagonist oral anticoagulants: inside and outside table cells

The opinion is expressed in some domestic publications that rivaroxaban has the most favorable profile of drug interaction in comparison to other non-vitamin K antagonist oral anticoagulants (NOAC). The basis for such judgments is the summary table of drug interaction from the 2015 practical guide o...

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Main Authors: Sergey Nikolaevich Bel'diev, Irina Vladimirovna Medvedeva, Dmitry Jur'evich Platonov
Format: Article
Language:English
Published: Столичная издательская компания 2017-11-01
Series:Рациональная фармакотерапия в кардиологии
Subjects:
Online Access:https://www.rpcardio.com/jour/article/view/1462
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author Sergey Nikolaevich Bel'diev
Irina Vladimirovna Medvedeva
Dmitry Jur'evich Platonov
author_facet Sergey Nikolaevich Bel'diev
Irina Vladimirovna Medvedeva
Dmitry Jur'evich Platonov
author_sort Sergey Nikolaevich Bel'diev
collection DOAJ
description The opinion is expressed in some domestic publications that rivaroxaban has the most favorable profile of drug interaction in comparison to other non-vitamin K antagonist oral anticoagulants (NOAC). The basis for such judgments is the summary table of drug interaction from the 2015 practical guide of the European Heart Rhythm Association on the use of NOAC in patients with non-valvular atrial fibrillation.The paper discusses the issue that the above table contains some incorrect qualitative statements and quantitative data inconsistent with primary sources on NOAC drug interactions, and provides the updated and extended information on changes in NOAC plasma concentrations when co-administered with drugs from the other groups. On the basis of the presented data, the authors come to the conclusion that the profile of drug interaction of rivaroxaban does not differ significantly from the other NOAC.
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spelling doaj.art-fdc739e3174e40f79b16544ae46628e42023-10-16T11:32:12ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532017-11-011351997Drug interactions of non-vitamin K antagonist oral anticoagulants: inside and outside table cellsSergey Nikolaevich Bel'diev0Irina Vladimirovna Medvedeva1Dmitry Jur'evich Platonov2Tver State Medical UniversityTver State Medical UniversityTver State Medical UniversityThe opinion is expressed in some domestic publications that rivaroxaban has the most favorable profile of drug interaction in comparison to other non-vitamin K antagonist oral anticoagulants (NOAC). The basis for such judgments is the summary table of drug interaction from the 2015 practical guide of the European Heart Rhythm Association on the use of NOAC in patients with non-valvular atrial fibrillation.The paper discusses the issue that the above table contains some incorrect qualitative statements and quantitative data inconsistent with primary sources on NOAC drug interactions, and provides the updated and extended information on changes in NOAC plasma concentrations when co-administered with drugs from the other groups. On the basis of the presented data, the authors come to the conclusion that the profile of drug interaction of rivaroxaban does not differ significantly from the other NOAC.https://www.rpcardio.com/jour/article/view/1462dabigatran, apixaban, rivaroxaban, edoxaban, drug interactions
spellingShingle Sergey Nikolaevich Bel'diev
Irina Vladimirovna Medvedeva
Dmitry Jur'evich Platonov
Drug interactions of non-vitamin K antagonist oral anticoagulants: inside and outside table cells
Рациональная фармакотерапия в кардиологии
dabigatran, apixaban, rivaroxaban, edoxaban, drug interactions
title Drug interactions of non-vitamin K antagonist oral anticoagulants: inside and outside table cells
title_full Drug interactions of non-vitamin K antagonist oral anticoagulants: inside and outside table cells
title_fullStr Drug interactions of non-vitamin K antagonist oral anticoagulants: inside and outside table cells
title_full_unstemmed Drug interactions of non-vitamin K antagonist oral anticoagulants: inside and outside table cells
title_short Drug interactions of non-vitamin K antagonist oral anticoagulants: inside and outside table cells
title_sort drug interactions of non vitamin k antagonist oral anticoagulants inside and outside table cells
topic dabigatran, apixaban, rivaroxaban, edoxaban, drug interactions
url https://www.rpcardio.com/jour/article/view/1462
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AT irinavladimirovnamedvedeva druginteractionsofnonvitaminkantagonistoralanticoagulantsinsideandoutsidetablecells
AT dmitryjurevichplatonov druginteractionsofnonvitaminkantagonistoralanticoagulantsinsideandoutsidetablecells