Hantavirus in Panama: Twenty Years of Epidemiological Surveillance Experience
Twenty years have passed since the emergence of hantavirus zoonosis in Panama at the beginning of this millennium. We provide an overview of epidemiological surveillance of hantavirus disease (hantavirus pulmonary syndrome and hantavirus fever) during the period 1999–2019 by including all reported a...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-06-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/15/6/1395 |
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| author | Blas Armién Carlos Muñoz Hector Cedeño Jacqueline R. Salazar Tybbyssay P. Salinas Publio González José Trujillo Deyanira Sánchez Jamileth Mariñas Ayvar Hernández Harmodio Cruz Leisy Yovany Villarreal Elba Grimaldo Samuel González Heydy Nuñez Susana Hesse Fernando Rivera George Edwards Ricardo Chong Ovidio Mendoza Martín Meza Milagro Herrera Rudick Kant Raul Esquivel Dora Estripeaut Demetrio Serracín Bernardino Denis Esthefani Robles Yaxelis Mendoza Gloria Gonzalez Felicia Tulloch Juan Miguel Pascale Jonathan L. Dunnum Joseph A. Cook Anibal G. Armién Fernando Gracia Gladys Alicia Guerrero Itza de Mosca |
| author_facet | Blas Armién Carlos Muñoz Hector Cedeño Jacqueline R. Salazar Tybbyssay P. Salinas Publio González José Trujillo Deyanira Sánchez Jamileth Mariñas Ayvar Hernández Harmodio Cruz Leisy Yovany Villarreal Elba Grimaldo Samuel González Heydy Nuñez Susana Hesse Fernando Rivera George Edwards Ricardo Chong Ovidio Mendoza Martín Meza Milagro Herrera Rudick Kant Raul Esquivel Dora Estripeaut Demetrio Serracín Bernardino Denis Esthefani Robles Yaxelis Mendoza Gloria Gonzalez Felicia Tulloch Juan Miguel Pascale Jonathan L. Dunnum Joseph A. Cook Anibal G. Armién Fernando Gracia Gladys Alicia Guerrero Itza de Mosca |
| author_sort | Blas Armién |
| collection | DOAJ |
| description | Twenty years have passed since the emergence of hantavirus zoonosis in Panama at the beginning of this millennium. We provide an overview of epidemiological surveillance of hantavirus disease (hantavirus pulmonary syndrome and hantavirus fever) during the period 1999–2019 by including all reported and confirmed cases according to the case definition established by the health authority. Our findings reveal that hantavirus disease is a low-frequency disease, affecting primarily young people, with a relatively low case-fatality rate compared to other hantaviruses in the Americas (e.g., ANDV and SNV). It presents an annual variation with peaks every 4–5 years and an interannual variation influenced by agricultural activities. Hantavirus disease is endemic in about 27% of Panama, which corresponds to agroecological conditions that favor the population dynamics of the rodent host, <i>Oligoryzomys costaricensis</i> and the virus (<i>Choclo orthohantavirus</i>) responsible for hantavirus disease. However, this does not rule out the existence of other endemic areas to be characterized. Undoubtedly, decentralization of the laboratory test and dissemination of evidence-based surveillance guidelines and regulations have standardized and improved diagnosis, notification at the level of the primary care system, and management in intensive care units nationwide. |
| first_indexed | 2024-03-11T01:50:36Z |
| format | Article |
| id | doaj.art-fdc9385ea50f486ea0a3b2090c1d9cda |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-11T01:50:36Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-fdc9385ea50f486ea0a3b2090c1d9cda2023-11-18T13:03:14ZengMDPI AGViruses1999-49152023-06-01156139510.3390/v15061395Hantavirus in Panama: Twenty Years of Epidemiological Surveillance ExperienceBlas Armién0Carlos Muñoz1Hector Cedeño2Jacqueline R. Salazar3Tybbyssay P. Salinas4Publio González5José Trujillo6Deyanira Sánchez7Jamileth Mariñas8Ayvar Hernández9Harmodio Cruz10Leisy Yovany Villarreal11Elba Grimaldo12Samuel González13Heydy Nuñez14Susana Hesse15Fernando Rivera16George Edwards17Ricardo Chong18Ovidio Mendoza19Martín Meza20Milagro Herrera21Rudick Kant22Raul Esquivel23Dora Estripeaut24Demetrio Serracín25Bernardino Denis26Esthefani Robles27Yaxelis Mendoza28Gloria Gonzalez29Felicia Tulloch30Juan Miguel Pascale31Jonathan L. Dunnum32Joseph A. Cook33Anibal G. Armién34Fernando Gracia35Gladys Alicia Guerrero36Itza de Mosca37Department of Research in Emerging and Zoonotic Infectious Diseases, Gorgas Memorial Institute of Health Studies, Panama City 0816-02593, PanamaDepartment of Epidemiology, Health Region of Los Santos, Ministry of Health, Las Tablas, Los Santos 0816-06812, PanamaNational Department of Epidemiology, Ministry of Health, Panama City 0816-06812, PanamaDepartment of Research in Emerging and Zoonotic Infectious Diseases, Gorgas Memorial Institute of Health Studies, Panama City 0816-02593, PanamaDepartment of Research in Emerging and Zoonotic Infectious Diseases, Gorgas Memorial Institute of Health Studies, Panama City 0816-02593, PanamaDepartment of Research in Emerging and Zoonotic Infectious Diseases, Gorgas Memorial Institute of Health Studies, Panama City 0816-02593, PanamaHospital Gustavo Nelson Collado, Caja de Seguro Social, Chitre, Herrera 0816-06808, PanamaHospital Rural de Tonosí, Ministerio de Salud, Tonosi, Los Santos 0816-06812, PanamaHospital Rural de Tonosí, Ministerio de Salud, Tonosi, Los Santos 0816-06812, PanamaHospital Rural de Tonosí, Ministerio de Salud, Tonosi, Los Santos 0816-06812, PanamaHospital Rural de Tonosí, Ministerio de Salud, Tonosi, Los Santos 0816-06812, PanamaHospital Rural de Tonosí, Ministerio de Salud, Tonosi, Los Santos 0816-06812, PanamaHospital Joaquín Pablo Franco Sayas, Ministry of Health, Las Tablas, Los Santos 0816-06812, PanamaHospital Gustavo Nelson Collado, Caja de Seguro Social, Chitre, Herrera 0816-06808, PanamaHospital Ezequiel Abadía, Caja de Seguro Social, Soná, Veraguas 0816-06808, PanamaHospital Dr. Luis Chicho Fábrega, Ministry of Health, Santiago, Veraguas 0816-06812, PanamaHospital Dr. Luis Chicho Fábrega, Ministry of Health, Santiago, Veraguas 0816-06812, PanamaHospital Dr. Luis Chicho Fábrega, Ministry of Health, Santiago, Veraguas 0816-06812, PanamaDepartment of Epidemiology, Health Region of Veraguas, Ministry of Health, Santiago, Veraguas 0816-06812, PanamaDepartment of Epidemiology, Health Region of Veraguas, Ministry of Health, Santiago, Veraguas 0816-06812, PanamaDepartment of Epidemiology, Health Region of Herrera, Ministry of Health, Chitre, Herrera 0816-06812, PanamaHospital Regional Rafael Estevez, Caja de Seguro Social, Aguadulce, Coclé 0816-06808, PanamaDepartment of Epidemiology of the Caja de Seguro Social, Panama City 0816-06808, PanamaHospital del Niño José Renal Esquivel, Panama City 0816-00383, PanamaSistema Nacional de Investigación (SNI), Secretaria Nacional de Ciencia y Tecnología (SENACYT), Panama City 0816-02852, PanamaDepartment of Research in Emerging and Zoonotic Infectious Diseases, Gorgas Memorial Institute of Health Studies, Panama City 0816-02593, PanamaDepartment of Research in Emerging and Zoonotic Infectious Diseases, Gorgas Memorial Institute of Health Studies, Panama City 0816-02593, PanamaDepartment of Research in Emerging and Zoonotic Infectious Diseases, Gorgas Memorial Institute of Health Studies, Panama City 0816-02593, PanamaSistema Nacional de Investigación (SNI), Secretaria Nacional de Ciencia y Tecnología (SENACYT), Panama City 0816-02852, PanamaDepartment of Genomics and Proteomics, Gorgas Memorial Institute of Health Studies, Panama City 0816-02593, PanamaHospital Santo Tomás, Panama City 0816-05602, PanamaDepartment of Genomics and Proteomics, Gorgas Memorial Institute of Health Studies, Panama City 0816-02593, PanamaDepartment of Biology and Museum of Southwestern Biology, University of New Mexico, Albuquerque, NM 87131, USADepartment of Biology and Museum of Southwestern Biology, University of New Mexico, Albuquerque, NM 87131, USACalifornia Animal Health & Food Safety Laboratory System (CAHFS), School of Veterinary Medicine, University of California, Davis, CA 95616, USAHospital Santo Tomás, Panama City 0816-05602, PanamaDepartment of Epidemiology of the Caja de Seguro Social, Panama City 0816-06808, PanamaNational Department of Epidemiology, Ministry of Health, Panama City 0816-06812, PanamaTwenty years have passed since the emergence of hantavirus zoonosis in Panama at the beginning of this millennium. We provide an overview of epidemiological surveillance of hantavirus disease (hantavirus pulmonary syndrome and hantavirus fever) during the period 1999–2019 by including all reported and confirmed cases according to the case definition established by the health authority. Our findings reveal that hantavirus disease is a low-frequency disease, affecting primarily young people, with a relatively low case-fatality rate compared to other hantaviruses in the Americas (e.g., ANDV and SNV). It presents an annual variation with peaks every 4–5 years and an interannual variation influenced by agricultural activities. Hantavirus disease is endemic in about 27% of Panama, which corresponds to agroecological conditions that favor the population dynamics of the rodent host, <i>Oligoryzomys costaricensis</i> and the virus (<i>Choclo orthohantavirus</i>) responsible for hantavirus disease. However, this does not rule out the existence of other endemic areas to be characterized. Undoubtedly, decentralization of the laboratory test and dissemination of evidence-based surveillance guidelines and regulations have standardized and improved diagnosis, notification at the level of the primary care system, and management in intensive care units nationwide.https://www.mdpi.com/1999-4915/15/6/1395<i>Choclo orthohantavirus</i>hantavirus diseasehantavirus pulmonary syndrome<i>Oligoryzomys costaricensis</i> (<i>=fulvescens</i>)hantavirus feverepidemiologic surveillance |
| spellingShingle | Blas Armién Carlos Muñoz Hector Cedeño Jacqueline R. Salazar Tybbyssay P. Salinas Publio González José Trujillo Deyanira Sánchez Jamileth Mariñas Ayvar Hernández Harmodio Cruz Leisy Yovany Villarreal Elba Grimaldo Samuel González Heydy Nuñez Susana Hesse Fernando Rivera George Edwards Ricardo Chong Ovidio Mendoza Martín Meza Milagro Herrera Rudick Kant Raul Esquivel Dora Estripeaut Demetrio Serracín Bernardino Denis Esthefani Robles Yaxelis Mendoza Gloria Gonzalez Felicia Tulloch Juan Miguel Pascale Jonathan L. Dunnum Joseph A. Cook Anibal G. Armién Fernando Gracia Gladys Alicia Guerrero Itza de Mosca Hantavirus in Panama: Twenty Years of Epidemiological Surveillance Experience Viruses <i>Choclo orthohantavirus</i> hantavirus disease hantavirus pulmonary syndrome <i>Oligoryzomys costaricensis</i> (<i>=fulvescens</i>) hantavirus fever epidemiologic surveillance |
| title | Hantavirus in Panama: Twenty Years of Epidemiological Surveillance Experience |
| title_full | Hantavirus in Panama: Twenty Years of Epidemiological Surveillance Experience |
| title_fullStr | Hantavirus in Panama: Twenty Years of Epidemiological Surveillance Experience |
| title_full_unstemmed | Hantavirus in Panama: Twenty Years of Epidemiological Surveillance Experience |
| title_short | Hantavirus in Panama: Twenty Years of Epidemiological Surveillance Experience |
| title_sort | hantavirus in panama twenty years of epidemiological surveillance experience |
| topic | <i>Choclo orthohantavirus</i> hantavirus disease hantavirus pulmonary syndrome <i>Oligoryzomys costaricensis</i> (<i>=fulvescens</i>) hantavirus fever epidemiologic surveillance |
| url | https://www.mdpi.com/1999-4915/15/6/1395 |
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