Neurological presentation of Whipple's disease after long-term antibiotic treatment: a case report
<p>Abstract</p> <p>Introduction</p> <p>Whipple's disease is a rare systemic infectious disorder caused by <it>Tropheryma whipplei</it>.</p> <p>Case presentation</p> <p>We report a 68-year-old male with Whipple's disease of t...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-06-01
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| Series: | Journal of Medical Case Reports |
| Online Access: | http://www.jmedicalcasereports.com/content/2/1/191 |
| _version_ | 1818363420075884544 |
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| author | Gundling Felix Wittenburg Henning Tannapfel Andrea Mossner Joachim |
| author_facet | Gundling Felix Wittenburg Henning Tannapfel Andrea Mossner Joachim |
| author_sort | Gundling Felix |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Introduction</p> <p>Whipple's disease is a rare systemic infectious disorder caused by <it>Tropheryma whipplei</it>.</p> <p>Case presentation</p> <p>We report a 68-year-old male with Whipple's disease of the central nervous system following long-term antibiotic therapy and many years after the initial clinical onset.</p> <p>Conclusion</p> <p>The combination of trimethoprim and sulphamethoxazole does not prevent or cure involvement of the central nervous system in all patients with Whipple's disease. If relapse of the central nervous system occurs treatment with meropenem might be a useful alternative.</p> |
| first_indexed | 2024-12-13T21:48:11Z |
| format | Article |
| id | doaj.art-fdc980ff00e54dddbbc1f5c7ace4116b |
| institution | Directory Open Access Journal |
| issn | 1752-1947 |
| language | English |
| last_indexed | 2024-12-13T21:48:11Z |
| publishDate | 2008-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj.art-fdc980ff00e54dddbbc1f5c7ace4116b2022-12-21T23:30:22ZengBMCJournal of Medical Case Reports1752-19472008-06-012119110.1186/1752-1947-2-191Neurological presentation of Whipple's disease after long-term antibiotic treatment: a case reportGundling FelixWittenburg HenningTannapfel AndreaMossner Joachim<p>Abstract</p> <p>Introduction</p> <p>Whipple's disease is a rare systemic infectious disorder caused by <it>Tropheryma whipplei</it>.</p> <p>Case presentation</p> <p>We report a 68-year-old male with Whipple's disease of the central nervous system following long-term antibiotic therapy and many years after the initial clinical onset.</p> <p>Conclusion</p> <p>The combination of trimethoprim and sulphamethoxazole does not prevent or cure involvement of the central nervous system in all patients with Whipple's disease. If relapse of the central nervous system occurs treatment with meropenem might be a useful alternative.</p>http://www.jmedicalcasereports.com/content/2/1/191 |
| spellingShingle | Gundling Felix Wittenburg Henning Tannapfel Andrea Mossner Joachim Neurological presentation of Whipple's disease after long-term antibiotic treatment: a case report Journal of Medical Case Reports |
| title | Neurological presentation of Whipple's disease after long-term antibiotic treatment: a case report |
| title_full | Neurological presentation of Whipple's disease after long-term antibiotic treatment: a case report |
| title_fullStr | Neurological presentation of Whipple's disease after long-term antibiotic treatment: a case report |
| title_full_unstemmed | Neurological presentation of Whipple's disease after long-term antibiotic treatment: a case report |
| title_short | Neurological presentation of Whipple's disease after long-term antibiotic treatment: a case report |
| title_sort | neurological presentation of whipple s disease after long term antibiotic treatment a case report |
| url | http://www.jmedicalcasereports.com/content/2/1/191 |
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