PD-1-mediated inhibition of T cell activation: Mechanisms and strategies for cancer combination immunotherapy
The programmed cell death 1 (PD-1) immune checkpoint of co-inhibitory signaling plays crucial roles in controlling the magnitude and duration of T cell activation to limit tissue damage and maintain self-tolerance. Cancer cells hijack the co-inhibitory pathway and escape immune surveillance by overe...
| Үндсэн зохиолчид: | , , |
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| Формат: | Өгүүллэг |
| Хэл сонгох: | English |
| Хэвлэсэн: |
Elsevier
2024-04-01
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| Цуврал: | Cell Insight |
| Онлайн хандалт: | http://www.sciencedirect.com/science/article/pii/S2772892724000014 |