Patients With Systemic Reaction to Their Hernia Mesh: An Introduction to Mesh Implant Illness

In our practice, we have noticed an increased number of patients requiring mesh removal due to a systemic reaction to their implant. We present our experience in diagnosing and treating a subpopulation of patients who require mesh removal due to a possible mesh implant illness (MII). All patients wh...

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Main Authors: Negin Fadaee, Desmond Huynh, Zayan Khanmohammed, Laura Mazer, Isabel Capati, Shirin Towfigh
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Journal of Abdominal Wall Surgery
Subjects:
Online Access:https://www.frontierspartnerships.org/articles/10.3389/jaws.2023.10983/full
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author Negin Fadaee
Desmond Huynh
Zayan Khanmohammed
Laura Mazer
Isabel Capati
Shirin Towfigh
author_facet Negin Fadaee
Desmond Huynh
Zayan Khanmohammed
Laura Mazer
Isabel Capati
Shirin Towfigh
author_sort Negin Fadaee
collection DOAJ
description In our practice, we have noticed an increased number of patients requiring mesh removal due to a systemic reaction to their implant. We present our experience in diagnosing and treating a subpopulation of patients who require mesh removal due to a possible mesh implant illness (MII). All patients who underwent mesh removal for indication of mesh reaction were captured from a hernia database. Data extraction focused on the patients’ predisposing medical conditions, presenting symptoms suggestive of mesh implant illness, types of implants to which reaction occurred, and postoperative outcome after mesh removal. Over almost 7 years, 165 patients had mesh removed. Indication for mesh removal was probable MII in 28 (17%). Most were in females (60%), average age was 46 years, with average pre-operative pain score 5.4/10. All patients underwent complete mesh removal. Sixteen (57%) required tissue repair of their hernia; 4 (14%) had hybrid mesh implanted. Nineteen (68%) had improvement and/or resolution of their MII symptoms within the first month after removal. We present insight into a unique but rising incidence of patients who suffer from systemic reaction following mesh implantation. Predisposing factors include female sex, history of autoimmune disorder, and multiple medical and environmental allergies and sensitivities. Presenting symptoms included spontaneous rashes, erythema and edema over the area of implant, arthralgia, headaches, and chronic fatigue. Long-term follow up after mesh removal confirmed resolution of symptoms after mesh removal. We hope this provides greater attention to patients who present with vague, non-specific but debilitating symptoms after mesh implantation.
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spelling doaj.art-fdcb8907463645c7957eceb5a04f5ba62023-03-03T14:50:21ZengFrontiers Media S.A.Journal of Abdominal Wall Surgery2813-20922023-01-01210.3389/jaws.2023.1098310983Patients With Systemic Reaction to Their Hernia Mesh: An Introduction to Mesh Implant IllnessNegin Fadaee0Desmond Huynh1Zayan Khanmohammed2Laura Mazer3Isabel Capati4Shirin Towfigh5California Health Sciences University College of Osteopathic Medicine, Clovis, CA, United StatesCedars-Sinai Medical Center, Los Angeles, CA, United StatesDepartment of Surgery, University of California, Berkeley, Berkeley, CA, United StatesHigher Ground Education, Lake Forest, CA, United StatesBeverly Hills Hernia Center, Beverly Hills, CA, United StatesBeverly Hills Hernia Center, Beverly Hills, CA, United StatesIn our practice, we have noticed an increased number of patients requiring mesh removal due to a systemic reaction to their implant. We present our experience in diagnosing and treating a subpopulation of patients who require mesh removal due to a possible mesh implant illness (MII). All patients who underwent mesh removal for indication of mesh reaction were captured from a hernia database. Data extraction focused on the patients’ predisposing medical conditions, presenting symptoms suggestive of mesh implant illness, types of implants to which reaction occurred, and postoperative outcome after mesh removal. Over almost 7 years, 165 patients had mesh removed. Indication for mesh removal was probable MII in 28 (17%). Most were in females (60%), average age was 46 years, with average pre-operative pain score 5.4/10. All patients underwent complete mesh removal. Sixteen (57%) required tissue repair of their hernia; 4 (14%) had hybrid mesh implanted. Nineteen (68%) had improvement and/or resolution of their MII symptoms within the first month after removal. We present insight into a unique but rising incidence of patients who suffer from systemic reaction following mesh implantation. Predisposing factors include female sex, history of autoimmune disorder, and multiple medical and environmental allergies and sensitivities. Presenting symptoms included spontaneous rashes, erythema and edema over the area of implant, arthralgia, headaches, and chronic fatigue. Long-term follow up after mesh removal confirmed resolution of symptoms after mesh removal. We hope this provides greater attention to patients who present with vague, non-specific but debilitating symptoms after mesh implantation.https://www.frontierspartnerships.org/articles/10.3389/jaws.2023.10983/fullmeshallergymesh reactionmesh removalmesh-ASIAhernia mesh
spellingShingle Negin Fadaee
Desmond Huynh
Zayan Khanmohammed
Laura Mazer
Isabel Capati
Shirin Towfigh
Patients With Systemic Reaction to Their Hernia Mesh: An Introduction to Mesh Implant Illness
Journal of Abdominal Wall Surgery
mesh
allergy
mesh reaction
mesh removal
mesh-ASIA
hernia mesh
title Patients With Systemic Reaction to Their Hernia Mesh: An Introduction to Mesh Implant Illness
title_full Patients With Systemic Reaction to Their Hernia Mesh: An Introduction to Mesh Implant Illness
title_fullStr Patients With Systemic Reaction to Their Hernia Mesh: An Introduction to Mesh Implant Illness
title_full_unstemmed Patients With Systemic Reaction to Their Hernia Mesh: An Introduction to Mesh Implant Illness
title_short Patients With Systemic Reaction to Their Hernia Mesh: An Introduction to Mesh Implant Illness
title_sort patients with systemic reaction to their hernia mesh an introduction to mesh implant illness
topic mesh
allergy
mesh reaction
mesh removal
mesh-ASIA
hernia mesh
url https://www.frontierspartnerships.org/articles/10.3389/jaws.2023.10983/full
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