Role of cytotoxic T cells and PD-1 immune checkpoint pathway in papillary thyroid carcinoma

Role of cytotoxic T cells and PD-1 immune checkpoint pathway in papillary thyroid carcinoma

BackgroundLymphocytic thyroiditis (LT) is frequently seen in the tumor microenvironment (TME) of papillary thyroid carcinomas (PTCs). However, the characteristic of these tumor-infiltrating lymphocytes (TILs) is not well understood.ObjectiveWe aim to define the TME of PTC cases by characterizing the...

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Bibliographic Details
Main Authors:	Sohini Banerjee, Uma Nahar, Divya Dahiya, Soham Mukherjee, Pranab Dey, Rijuneeta Gupta, Bishan Radotra, Naresh Sachdeva, Ashwani Sood, Sanjay Kumar Bhadada, Anil Bhansali
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-11-01
Series:	Frontiers in Endocrinology
Subjects:	papillary thyroid carcinoma tumor microenvironment programmed death-1 CD8 T cell anti tumor immunity
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2022.931647/full

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