What predicts large vessel occlusion in mild stroke patients?
Abstract Background and purpose Mild acute ischemic stroke (AIS) patients with large vessel occlusion (LVO) may benefit from thrombolysis or thrombectomy therapy. However, the predictors for LVO in mild AIS patients have not been extensively explored. We aimed to investigate the predictors for LVO i...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-01-01
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| Series: | BMC Neurology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12883-022-03020-6 |
| _version_ | 1797945849899122688 |
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| author | Zhengzhao Lu Yunyun Xiong Kaixuan Yang Hongqiu Gu Chunmiao Duan Xingquan Zhao Xia Meng Yongjun Wang |
| author_facet | Zhengzhao Lu Yunyun Xiong Kaixuan Yang Hongqiu Gu Chunmiao Duan Xingquan Zhao Xia Meng Yongjun Wang |
| author_sort | Zhengzhao Lu |
| collection | DOAJ |
| description | Abstract Background and purpose Mild acute ischemic stroke (AIS) patients with large vessel occlusion (LVO) may benefit from thrombolysis or thrombectomy therapy. However, the predictors for LVO in mild AIS patients have not been extensively explored. We aimed to investigate the predictors for LVO in mild AIS patients. Methods We collected the data of consecutive AIS patients with a National Institutes of Health Stroke Scale (NIHSS) score ≤ 5 from The Third China National Stroke Registry - a prospective nationwide registry of AIS or transient ischemic attack (TIA) patients in China from August 2015 to March 2018. Patients were divided into LVO and non-LVO group based on the vascular imaging during the hospitalization. Multivariable regression analyses involving clinical characteristics and NIHSS subitems was performed to detect the predictors for LVO. Result A total of 7653 mild AIS patients from The Third China National Stroke Registry were included in this study. Among them, 620 patients (8.1%) had LVO. The level of consciousness (adjusted odds ratio, 1.87; 95% confidence interval, 1.08 to 3.23), visual field (adjusted odds ratio, 2.10; 95% confidence interval, 1.43 to 3.06) and sensory (adjusted odds ratio, 0.75; 95% confidence interval, 0.60 to 0.94) were predictors for mild AIS patients with LVO. Conclusions Impaired LOC, visual field and sensory were independently predictors for LVO in mild stroke patients. Further studies are warranted to test these predictors in prehospital setting and in other population. |
| first_indexed | 2024-04-10T21:02:43Z |
| format | Article |
| id | doaj.art-fdcff2b43b214d12883c69d6b1448975 |
| institution | Directory Open Access Journal |
| issn | 1471-2377 |
| language | English |
| last_indexed | 2024-04-10T21:02:43Z |
| publishDate | 2023-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Neurology |
| spelling | doaj.art-fdcff2b43b214d12883c69d6b14489752023-01-22T12:17:39ZengBMCBMC Neurology1471-23772023-01-012311810.1186/s12883-022-03020-6What predicts large vessel occlusion in mild stroke patients?Zhengzhao Lu0Yunyun Xiong1Kaixuan Yang2Hongqiu Gu3Chunmiao Duan4Xingquan Zhao5Xia Meng6Yongjun Wang7Department of Neurology, Beijing Tiantan Hospital, Capital Medical UniversityDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical UniversityChina National Clinical Research Center for Neurological DiseasesChina National Clinical Research Center for Neurological DiseasesDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical UniversityDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical UniversityChina National Clinical Research Center for Neurological DiseasesDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical UniversityAbstract Background and purpose Mild acute ischemic stroke (AIS) patients with large vessel occlusion (LVO) may benefit from thrombolysis or thrombectomy therapy. However, the predictors for LVO in mild AIS patients have not been extensively explored. We aimed to investigate the predictors for LVO in mild AIS patients. Methods We collected the data of consecutive AIS patients with a National Institutes of Health Stroke Scale (NIHSS) score ≤ 5 from The Third China National Stroke Registry - a prospective nationwide registry of AIS or transient ischemic attack (TIA) patients in China from August 2015 to March 2018. Patients were divided into LVO and non-LVO group based on the vascular imaging during the hospitalization. Multivariable regression analyses involving clinical characteristics and NIHSS subitems was performed to detect the predictors for LVO. Result A total of 7653 mild AIS patients from The Third China National Stroke Registry were included in this study. Among them, 620 patients (8.1%) had LVO. The level of consciousness (adjusted odds ratio, 1.87; 95% confidence interval, 1.08 to 3.23), visual field (adjusted odds ratio, 2.10; 95% confidence interval, 1.43 to 3.06) and sensory (adjusted odds ratio, 0.75; 95% confidence interval, 0.60 to 0.94) were predictors for mild AIS patients with LVO. Conclusions Impaired LOC, visual field and sensory were independently predictors for LVO in mild stroke patients. Further studies are warranted to test these predictors in prehospital setting and in other population.https://doi.org/10.1186/s12883-022-03020-6Emergency medical servicesThrombectomyIschemic strokeEpidemiologyClinical decision making |
| spellingShingle | Zhengzhao Lu Yunyun Xiong Kaixuan Yang Hongqiu Gu Chunmiao Duan Xingquan Zhao Xia Meng Yongjun Wang What predicts large vessel occlusion in mild stroke patients? BMC Neurology Emergency medical services Thrombectomy Ischemic stroke Epidemiology Clinical decision making |
| title | What predicts large vessel occlusion in mild stroke patients? |
| title_full | What predicts large vessel occlusion in mild stroke patients? |
| title_fullStr | What predicts large vessel occlusion in mild stroke patients? |
| title_full_unstemmed | What predicts large vessel occlusion in mild stroke patients? |
| title_short | What predicts large vessel occlusion in mild stroke patients? |
| title_sort | what predicts large vessel occlusion in mild stroke patients |
| topic | Emergency medical services Thrombectomy Ischemic stroke Epidemiology Clinical decision making |
| url | https://doi.org/10.1186/s12883-022-03020-6 |
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