Progress of Epigenetic Methylation in Lung Cancer Research
Lung cancer is becoming an increasing threat to Chinese residents and its incidence continues to rise while the treatment effect is far from satisfactory. Hence, it is essential to improve the level of early diagnosis, treatment, prognosis in lung cancer. An epigenetic trait is a stably heritable ph...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Chinese Anti-Cancer Association; Chinese Antituberculosis Association
2017-09-01
|
| Series: | Chinese Journal of Lung Cancer |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.3779/j.issn.1009-3419.2017.09.08 |
| _version_ | 1811269902949941248 |
|---|---|
| author | Shaowei ZHANG Zhiqiang XUE |
| author_facet | Shaowei ZHANG Zhiqiang XUE |
| author_sort | Shaowei ZHANG |
| collection | DOAJ |
| description | Lung cancer is becoming an increasing threat to Chinese residents and its incidence continues to rise while the treatment effect is far from satisfactory. Hence, it is essential to improve the level of early diagnosis, treatment, prognosis in lung cancer. An epigenetic trait is a stably heritable phenotype resulting from changes in a chromosome without alterations in the DNA sequence. The epigenetic studies, such as DNA methylation and histone methylation, are progressing rapidly in oncology research. A comprehensive understanding of its development status and existing problems is of great significance for the future research and the implementation of precision medicine. Herein, we aim to outline the progress of DNA methylation and histone methylation modification in lung cancer and make a prospect for the future research. |
| first_indexed | 2024-04-12T21:51:27Z |
| format | Article |
| id | doaj.art-fdd224728a49477c9f1dd5ec674fa159 |
| institution | Directory Open Access Journal |
| issn | 1009-3419 1999-6187 |
| language | zho |
| last_indexed | 2024-04-12T21:51:27Z |
| publishDate | 2017-09-01 |
| publisher | Chinese Anti-Cancer Association; Chinese Antituberculosis Association |
| record_format | Article |
| series | Chinese Journal of Lung Cancer |
| spelling | doaj.art-fdd224728a49477c9f1dd5ec674fa1592022-12-22T03:15:29ZzhoChinese Anti-Cancer Association; Chinese Antituberculosis AssociationChinese Journal of Lung Cancer1009-34191999-61872017-09-0120963564010.3779/j.issn.1009-3419.2017.09.08Progress of Epigenetic Methylation in Lung Cancer ResearchShaowei ZHANG0Zhiqiang XUE1Department of Toracic Surgery, PLA General Hospital, Beijing 100853, ChinaDepartment of Toracic Surgery, PLA General Hospital, Beijing 100853, ChinaLung cancer is becoming an increasing threat to Chinese residents and its incidence continues to rise while the treatment effect is far from satisfactory. Hence, it is essential to improve the level of early diagnosis, treatment, prognosis in lung cancer. An epigenetic trait is a stably heritable phenotype resulting from changes in a chromosome without alterations in the DNA sequence. The epigenetic studies, such as DNA methylation and histone methylation, are progressing rapidly in oncology research. A comprehensive understanding of its development status and existing problems is of great significance for the future research and the implementation of precision medicine. Herein, we aim to outline the progress of DNA methylation and histone methylation modification in lung cancer and make a prospect for the future research.http://dx.doi.org/10.3779/j.issn.1009-3419.2017.09.08Lung neoplasmsDNA methylationMethylation of Histone codeEarly detection of cancerEpigenetic agentsPrecision medicine |
| spellingShingle | Shaowei ZHANG Zhiqiang XUE Progress of Epigenetic Methylation in Lung Cancer Research Chinese Journal of Lung Cancer Lung neoplasms DNA methylation Methylation of Histone code Early detection of cancer Epigenetic agents Precision medicine |
| title | Progress of Epigenetic Methylation in Lung Cancer Research |
| title_full | Progress of Epigenetic Methylation in Lung Cancer Research |
| title_fullStr | Progress of Epigenetic Methylation in Lung Cancer Research |
| title_full_unstemmed | Progress of Epigenetic Methylation in Lung Cancer Research |
| title_short | Progress of Epigenetic Methylation in Lung Cancer Research |
| title_sort | progress of epigenetic methylation in lung cancer research |
| topic | Lung neoplasms DNA methylation Methylation of Histone code Early detection of cancer Epigenetic agents Precision medicine |
| url | http://dx.doi.org/10.3779/j.issn.1009-3419.2017.09.08 |
| work_keys_str_mv | AT shaoweizhang progressofepigeneticmethylationinlungcancerresearch AT zhiqiangxue progressofepigeneticmethylationinlungcancerresearch |