Hypertension in Cardio-Oncology Clinic: an update on etiology, assessment, and management

Abstract Hypertension is one of the most common comorbidity and the leading cause of cancer-related death in cancer patients. The prevalence of hypertension in cancer patients is much higher than that of the general population. In the older population of cancer patients, specific cancer treatments s...

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Main Authors: Amir Askarinejad, Azin Alizadehasl, Amir Ghaffari Jolfayi, Sara Adimi
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Cardio-Oncology
Subjects:
Online Access:https://doi.org/10.1186/s40959-023-00197-8
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author Amir Askarinejad
Azin Alizadehasl
Amir Ghaffari Jolfayi
Sara Adimi
author_facet Amir Askarinejad
Azin Alizadehasl
Amir Ghaffari Jolfayi
Sara Adimi
author_sort Amir Askarinejad
collection DOAJ
description Abstract Hypertension is one of the most common comorbidity and the leading cause of cancer-related death in cancer patients. The prevalence of hypertension in cancer patients is much higher than that of the general population. In the older population of cancer patients, specific cancer treatments such as new tyrosine kinase inhibitors and Vascular endothelial growth factor inhibitor drugs give rise to hypertension in cancer patients; The aim of present study is to provide a detailed discussion etiologies of cancer treatment-induced hypertension and explore the most innovative diagnostic and management approaches. This review will address the optimal approach to hypertension treatment, covering treatment initiation thresholds, targets, and the selection of anti-hypertensive agents. The lack of evidence in recent guidelines for managing cardiovascular toxicities in cancer patients can create uncertainty in clinicians' therapeutic and clinical decisions. This review aims to enhance our understanding of hypertension etiology in cancer patients and provide a practical guide to current treatment approaches.
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spelling doaj.art-fdd4762f45f345aaa5d444d1c3a1632e2023-12-17T12:31:28ZengBMCCardio-Oncology2057-38042023-12-019111310.1186/s40959-023-00197-8Hypertension in Cardio-Oncology Clinic: an update on etiology, assessment, and managementAmir Askarinejad0Azin Alizadehasl1Amir Ghaffari Jolfayi2Sara Adimi3Rajaie Cardiovascular Medical and Research Center, Iran University of Medical SciencesCardio-Oncology Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical SciencesRajaie Cardiovascular Medical and Research Center, Iran University of Medical SciencesCardio-Oncology Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical SciencesAbstract Hypertension is one of the most common comorbidity and the leading cause of cancer-related death in cancer patients. The prevalence of hypertension in cancer patients is much higher than that of the general population. In the older population of cancer patients, specific cancer treatments such as new tyrosine kinase inhibitors and Vascular endothelial growth factor inhibitor drugs give rise to hypertension in cancer patients; The aim of present study is to provide a detailed discussion etiologies of cancer treatment-induced hypertension and explore the most innovative diagnostic and management approaches. This review will address the optimal approach to hypertension treatment, covering treatment initiation thresholds, targets, and the selection of anti-hypertensive agents. The lack of evidence in recent guidelines for managing cardiovascular toxicities in cancer patients can create uncertainty in clinicians' therapeutic and clinical decisions. This review aims to enhance our understanding of hypertension etiology in cancer patients and provide a practical guide to current treatment approaches.https://doi.org/10.1186/s40959-023-00197-8Cardio-oncologyHypertensionVascular endothelial growth factor inhibitorTyrosine kinase inhibitors
spellingShingle Amir Askarinejad
Azin Alizadehasl
Amir Ghaffari Jolfayi
Sara Adimi
Hypertension in Cardio-Oncology Clinic: an update on etiology, assessment, and management
Cardio-Oncology
Cardio-oncology
Hypertension
Vascular endothelial growth factor inhibitor
Tyrosine kinase inhibitors
title Hypertension in Cardio-Oncology Clinic: an update on etiology, assessment, and management
title_full Hypertension in Cardio-Oncology Clinic: an update on etiology, assessment, and management
title_fullStr Hypertension in Cardio-Oncology Clinic: an update on etiology, assessment, and management
title_full_unstemmed Hypertension in Cardio-Oncology Clinic: an update on etiology, assessment, and management
title_short Hypertension in Cardio-Oncology Clinic: an update on etiology, assessment, and management
title_sort hypertension in cardio oncology clinic an update on etiology assessment and management
topic Cardio-oncology
Hypertension
Vascular endothelial growth factor inhibitor
Tyrosine kinase inhibitors
url https://doi.org/10.1186/s40959-023-00197-8
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AT azinalizadehasl hypertensionincardiooncologyclinicanupdateonetiologyassessmentandmanagement
AT amirghaffarijolfayi hypertensionincardiooncologyclinicanupdateonetiologyassessmentandmanagement
AT saraadimi hypertensionincardiooncologyclinicanupdateonetiologyassessmentandmanagement