3-Arylaziridine-2-carboxylic Acid Derivatives and (3-Arylaziridin-2-yl)ketones: The Aziridination Approaches
Aziridination reactions represent a powerful tool in aziridine synthesis. Significant progress has been achieved in this field in the last decades, whereas highly functionalized aziridines including 3-arylated aziridine-2-carbonyl compounds play an important role in both medical and synthetic chemis...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-09-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/22/18/9861 |
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| author | Boriss Strumfs Romans Uljanovs Kirils Velikijs Peteris Trapencieris Ilze Strumfa |
| author_facet | Boriss Strumfs Romans Uljanovs Kirils Velikijs Peteris Trapencieris Ilze Strumfa |
| author_sort | Boriss Strumfs |
| collection | DOAJ |
| description | Aziridination reactions represent a powerful tool in aziridine synthesis. Significant progress has been achieved in this field in the last decades, whereas highly functionalized aziridines including 3-arylated aziridine-2-carbonyl compounds play an important role in both medical and synthetic chemistry. For the reasons listed, in the current review we have focused on the ways to obtain 3-arylated aziridines and on the recent advances (mainly since the year 2000) in the methodology of the synthesis of these compounds via aziridination. |
| first_indexed | 2024-03-10T07:36:21Z |
| format | Article |
| id | doaj.art-fdd484e8eb2747fa83cbad71f96d3435 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T07:36:21Z |
| publishDate | 2021-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-fdd484e8eb2747fa83cbad71f96d34352023-11-22T13:28:42ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-09-012218986110.3390/ijms221898613-Arylaziridine-2-carboxylic Acid Derivatives and (3-Arylaziridin-2-yl)ketones: The Aziridination ApproachesBoriss Strumfs0Romans Uljanovs1Kirils Velikijs2Peteris Trapencieris3Ilze Strumfa4Latvian Institute of Organic Synthesis, 21 Aizkraukles Street, LV-1006 Riga, LatviaDepartment of Pathology, Riga Stradins University, 16 Dzirciema Street, LV-1007 Riga, LatviaDepartment of Pathology, Riga Stradins University, 16 Dzirciema Street, LV-1007 Riga, LatviaLatvian Institute of Organic Synthesis, 21 Aizkraukles Street, LV-1006 Riga, LatviaDepartment of Pathology, Riga Stradins University, 16 Dzirciema Street, LV-1007 Riga, LatviaAziridination reactions represent a powerful tool in aziridine synthesis. Significant progress has been achieved in this field in the last decades, whereas highly functionalized aziridines including 3-arylated aziridine-2-carbonyl compounds play an important role in both medical and synthetic chemistry. For the reasons listed, in the current review we have focused on the ways to obtain 3-arylated aziridines and on the recent advances (mainly since the year 2000) in the methodology of the synthesis of these compounds via aziridination.https://www.mdpi.com/1422-0067/22/18/9861aziridinesaziridinationiminescarbenesnitrenes |
| spellingShingle | Boriss Strumfs Romans Uljanovs Kirils Velikijs Peteris Trapencieris Ilze Strumfa 3-Arylaziridine-2-carboxylic Acid Derivatives and (3-Arylaziridin-2-yl)ketones: The Aziridination Approaches International Journal of Molecular Sciences aziridines aziridination imines carbenes nitrenes |
| title | 3-Arylaziridine-2-carboxylic Acid Derivatives and (3-Arylaziridin-2-yl)ketones: The Aziridination Approaches |
| title_full | 3-Arylaziridine-2-carboxylic Acid Derivatives and (3-Arylaziridin-2-yl)ketones: The Aziridination Approaches |
| title_fullStr | 3-Arylaziridine-2-carboxylic Acid Derivatives and (3-Arylaziridin-2-yl)ketones: The Aziridination Approaches |
| title_full_unstemmed | 3-Arylaziridine-2-carboxylic Acid Derivatives and (3-Arylaziridin-2-yl)ketones: The Aziridination Approaches |
| title_short | 3-Arylaziridine-2-carboxylic Acid Derivatives and (3-Arylaziridin-2-yl)ketones: The Aziridination Approaches |
| title_sort | 3 arylaziridine 2 carboxylic acid derivatives and 3 arylaziridin 2 yl ketones the aziridination approaches |
| topic | aziridines aziridination imines carbenes nitrenes |
| url | https://www.mdpi.com/1422-0067/22/18/9861 |
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