Intravitreal aflibercept for management of subfoveal choroidal neovascularization secondary to angioid streaks
In this study, we reported the clinical results of switching from ranibizumab to aflibercept for the treatment of an insufficient responder with choroidal neovascularization (CNV) secondary to angioid streaks (AS). A 39-year-old female patient with CNV secondary to AS had bilateral persistent intrar...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2015;volume=63;issue=7;spage=616;epage=618;aulast=Esen |
| _version_ | 1819170917362696192 |
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| author | Ebru Esen Selçuk Sizmaz Nihal Demircan |
| author_facet | Ebru Esen Selçuk Sizmaz Nihal Demircan |
| author_sort | Ebru Esen |
| collection | DOAJ |
| description | In this study, we reported the clinical results of switching from ranibizumab to aflibercept for the treatment of an insufficient responder with choroidal neovascularization (CNV) secondary to angioid streaks (AS). A 39-year-old female patient with CNV secondary to AS had bilateral persistent intraretinal and subretinal fluid on the optical coherence tomography despite prior intravitreal 0.5 mg ranibizumab injections. The therapy was switched to intravitreal injection of aflibercept. The patient received a loading dose of three intravitreal 2 mg aflibercept injections at 4-week intervals for both eyes. Morphological and functional effects were observed as early as 1-week after the first injection. After the third aflibercept injection, her visual acuity improved, intraretinal and subretinal fluid resolved, and central macular thickness reduced in both eyes. This is an early, but encouraging and promising result indicating that aflibercept might be a good alternative management for CNV secondary to AS that is insufficiently responding to prior ranibizumab injections. |
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| format | Article |
| id | doaj.art-fdd6340d0e6c40e2a2b7795167d61c04 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-12-22T19:43:01Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-fdd6340d0e6c40e2a2b7795167d61c042022-12-21T18:14:46ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892015-01-0163761661810.4103/0301-4738.167121Intravitreal aflibercept for management of subfoveal choroidal neovascularization secondary to angioid streaksEbru EsenSelçuk SizmazNihal DemircanIn this study, we reported the clinical results of switching from ranibizumab to aflibercept for the treatment of an insufficient responder with choroidal neovascularization (CNV) secondary to angioid streaks (AS). A 39-year-old female patient with CNV secondary to AS had bilateral persistent intraretinal and subretinal fluid on the optical coherence tomography despite prior intravitreal 0.5 mg ranibizumab injections. The therapy was switched to intravitreal injection of aflibercept. The patient received a loading dose of three intravitreal 2 mg aflibercept injections at 4-week intervals for both eyes. Morphological and functional effects were observed as early as 1-week after the first injection. After the third aflibercept injection, her visual acuity improved, intraretinal and subretinal fluid resolved, and central macular thickness reduced in both eyes. This is an early, but encouraging and promising result indicating that aflibercept might be a good alternative management for CNV secondary to AS that is insufficiently responding to prior ranibizumab injections.http://www.ijo.in/article.asp?issn=0301-4738;year=2015;volume=63;issue=7;spage=616;epage=618;aulast=EsenAfliberceptangioid streakschoroidal neovascularization |
| spellingShingle | Ebru Esen Selçuk Sizmaz Nihal Demircan Intravitreal aflibercept for management of subfoveal choroidal neovascularization secondary to angioid streaks Indian Journal of Ophthalmology Aflibercept angioid streaks choroidal neovascularization |
| title | Intravitreal aflibercept for management of subfoveal choroidal neovascularization secondary to angioid streaks |
| title_full | Intravitreal aflibercept for management of subfoveal choroidal neovascularization secondary to angioid streaks |
| title_fullStr | Intravitreal aflibercept for management of subfoveal choroidal neovascularization secondary to angioid streaks |
| title_full_unstemmed | Intravitreal aflibercept for management of subfoveal choroidal neovascularization secondary to angioid streaks |
| title_short | Intravitreal aflibercept for management of subfoveal choroidal neovascularization secondary to angioid streaks |
| title_sort | intravitreal aflibercept for management of subfoveal choroidal neovascularization secondary to angioid streaks |
| topic | Aflibercept angioid streaks choroidal neovascularization |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2015;volume=63;issue=7;spage=616;epage=618;aulast=Esen |
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