Amyloidogenic and Neuroinflammatory Molecular Pathways Are Contrasted Using Menaquinone 4 (MK4) and Reduced Menaquinone 7 (MK7R) in Association with Increased DNA Methylation in SK-N-BE Neuroblastoma Cell Line

Amyloidogenic and Neuroinflammatory Molecular Pathways Are Contrasted Using Menaquinone 4 (MK4) and Reduced Menaquinone 7 (MK7R) in Association with Increased DNA Methylation in SK-N-BE Neuroblastoma Cell Line

Besides its role in coagulation, vitamin K seems to be involved in various other mechanisms, including inflammation and age-related diseases, also at the level of gene expression. This work examined the roles of two vitamin K2 (menaquinones) vitamers, namely, menaquinone-4 (MK4) and reduced menaquin...

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Bibliographic Details
Main Authors: Michela Orticello, Rosaria A. Cavallaro, Daniele Antinori, Tiziana Raia, Marco Lucarelli, Andrea Fuso
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cells
Subjects:
DNA methylation
gene expression regulation
vitamin K2
menaquinone derivatives
MK4
reduced MK7
Online Access:https://www.mdpi.com/2073-4409/13/1/58

Internet

https://www.mdpi.com/2073-4409/13/1/58

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