Endogenous Semaphorin-7A Impedes Human Lung Fibroblast Differentiation.

Endogenous Semaphorin-7A Impedes Human Lung Fibroblast Differentiation.

Semaphorin-7A is a glycosylphosphatidylinositol-anchored protein, initially characterized as an axon guidance protein. Semaphorin-7A also contributes to immune cell regulation and may be an essential pro-fibrotic factor when expressed by non-fibroblast cell types (exogenous). In mouse models, semaph...

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Bibliographic Details
Main Authors: Stephane Esnault, Elizabeth E Torr, Ksenija Bernau, Mats W Johansson, Elizabeth A Kelly, Nathan Sandbo, Nizar N Jarjour
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5240965?pdf=render

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