The Obesogenic and Glycemic Effect of Bariatric Surgery in a Family with a Melanocortin 4 Receptor Loss-of-Function Mutation

The Obesogenic and Glycemic Effect of Bariatric Surgery in a Family with a Melanocortin 4 Receptor Loss-of-Function Mutation

We report the long-term response to bariatric surgery in a singular family of four adolescents with severe obesity (41–82 kg/m<sup>2</sup>), homozygous for the C271R loss-of-function mutation in the melanocortin 4 receptor (MC4R), and three adults heterozygous for the same mutation. All...

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Bibliographic Details
Main Authors: Ronit Grinbaum, Nahum Beglaibter, Stella Mitrani-Rosenbaum, Lee M. Kaplan, Danny Ben-Zvi
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Metabolites
Subjects:
obesity
bariatric surgery
diabetes
OSA
melanocortin 4 receptor
Online Access:https://www.mdpi.com/2218-1989/12/5/430

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