Chronic Wasting Disease Agents in Nonhuman Primates

Chronic wasting disease is a prion disease of cervids. Assessment of its zoonotic potential is critical. To evaluate primate susceptibility, we tested monkeys from 2 genera. We found that 100% of intracerebrally inoculated and 92% of orally inoculated squirrel monkeys were susceptible, but cynomolgu...

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Bibliographic Details
Main Authors: Brent Race, Kimberly D. Meade-White, Katie Phillips, James Striebel, Richard Race, Bruce Chesebro
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2014-05-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/20/5/13-0778_article
Description
Summary:Chronic wasting disease is a prion disease of cervids. Assessment of its zoonotic potential is critical. To evaluate primate susceptibility, we tested monkeys from 2 genera. We found that 100% of intracerebrally inoculated and 92% of orally inoculated squirrel monkeys were susceptible, but cynomolgus macaques were not, suggesting possible low risk for humans.
ISSN:1080-6040
1080-6059